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The endocrine disruptors dibutyl phthalate (DBP) and diethylstilbestrol (DES) influence Leydig cell regeneration following ethane dimethane sulphonate treatment of adult male rats (2011)
Journal Article
Heng, K., Anand-Ivell, R., Teerds, K., & Ivell, R. (2012). The endocrine disruptors dibutyl phthalate (DBP) and diethylstilbestrol (DES) influence Leydig cell regeneration following ethane dimethane sulphonate treatment of adult male rats. International Journal of Andrology, 35(3), 353-363. https://doi.org/10.1111/j.1365-2605.2011.01231.x

The manner by which endocrine-disrupting xenobiotics, such as phthalates, can induce changes in the development of the male reproductive system still remains largely unknown. Herein, we have explored the application of ethane dimethane sulphonate (ED... Read More about The endocrine disruptors dibutyl phthalate (DBP) and diethylstilbestrol (DES) influence Leydig cell regeneration following ethane dimethane sulphonate treatment of adult male rats.

Biological role and clinical significance of insulin-like peptide 3 (2011)
Journal Article
Ivell, R., & Anand-Ivell, R. (2011). Biological role and clinical significance of insulin-like peptide 3. Current Opinion in Endocrinology, Diabetes and Obesity, 18(3), 210-216. https://doi.org/10.1097/MED.0b013e3283453fe6

Purpose of Review: Insulin-like peptide 3 (INSL3) is the subject of a fast expanding literature reflecting increasing clinical application, particularly as a diagnostic parameter. This review summarizes the recent INSL3 literature published within th... Read More about Biological role and clinical significance of insulin-like peptide 3.

The special systems biology of the sperm (2011)
Journal Article
Anand-Ivell, R., & Ivell, R. (2011). The special systems biology of the sperm. Biochemical Journal, 436(3), e3-e5. https://doi.org/10.1042/BJ20110766

Spermatozoa represent a highly specialized cell type, with a minimalist structure designed to fulfil a single principal function: the transport of an intact single-copy haploid genome to the site of fertilization in the oviduct, and consequent zygote... Read More about The special systems biology of the sperm.

INSL3 in the ruminant: A powerful indicator of gender- and genetic-specific feto-maternal dialogue (2011)
Journal Article
Anand-Ivell, R., Hiendleder, S., Viñoles, C., Martin, G. B., Fitzsimmons, C., Eurich, A., …Ivell, R. (2011). INSL3 in the ruminant: A powerful indicator of gender- and genetic-specific feto-maternal dialogue. PLoS ONE, 6(5), 1-7. https://doi.org/10.1371/journal.pone.0019821

The hormone Insulin-like peptide 3 (INSL3) is a major secretory product of the Leydig cells from both fetal and adult testes. Consequently, it is a major gender-specific circulating hormone in the male fetus, where it is responsible for the first pha... Read More about INSL3 in the ruminant: A powerful indicator of gender- and genetic-specific feto-maternal dialogue.