Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat

Jethwa, Preeti H.; Smith, Kirsty L.; Small, Caroline J.; Abbott, Caroline R.; Darch, Sarah J.; Murphy, Kevin G.; Seth, Asha; Semjonous, Nina M.; Patel, Sejal R.; Todd, Jeannie F.; Ghatei, Mohammad A.; Bloom, Stephen R.

doi:10.1210/en.2005-0983

Research Repository

All Outputs (2)

Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats (2006)
Journal Article

The kisspeptins are KiSS-1 gene-derived peptides that signal through the G protein-coupled receptor-54 (GPR54) and have recently been shown to be critical regulators of reproduction. Acute intracerebroventricular or peripheral administration of kissp... Read More about Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats.

Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat (2006)
Journal Article

Intracerebroventricular (ICV) administration of the hypothalamic neuropeptide neuromedin U (NMU) or the adipostat hormone leptin increases plasma ACTH and corticosterone. The relationship between leptin and NMU in the regulation of the hypothalamo-pi... Read More about Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat.