All Outputs (196)

Interventions for dysphagia in acute stroke (Review) (2008)
Journal Article
Bath, P. M., Bath-Hextall, F., & Smithard, D. (2008). Interventions for dysphagia in acute stroke (Review). Cochrane Library, 2008(3), https://doi.org/10.1002/14651858.CD000323

Background It is unclear how dysphagic patients should be fed and treated after acute stroke. Objectives The objective of this review was to assess the effect of different management strategies for dysphagic stroke patients, in particular how and... Read More about Interventions for dysphagia in acute stroke (Review).

Should data monitoring committees assess efficacy when considering safety in trails in acute stroke? (2007)
Journal Article
Bath, P. M., Gray, L. J., & Wahlgren, N. (2007). Should data monitoring committees assess efficacy when considering safety in trails in acute stroke?. International Journal of Clinical Practice, 61(10),

The primary role of a trials Data Monitoring Committee (DMC) is to ensure the safety of enrolled patients. In stroke trials, safety is monitored typically by comparing death and stroke specific events between treatment groups. DMCs may also have the... Read More about Should data monitoring committees assess efficacy when considering safety in trails in acute stroke?.

Sex differences in quality of life in stroke survivors. Data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST) (2007)
Journal Article
Gray, L. J., Sprigg, N., Bath, P. M., Boysen, G., De Deyn, P. P., Leys, D., O'Neill, D., & Ringelstein, B. (2007). Sex differences in quality of life in stroke survivors. Data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST). Stroke, 38, https://doi.org/10.1161/STROKEAHA.107.488304

Introduction: Female sex is predictive of poor functional outcome in stroke, even after correction for prognostic factors. Poor quality of life (QoL) is observed in stroke survivors, with lower scores seen in the most disabled patients. We used data... Read More about Sex differences in quality of life in stroke survivors. Data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST).

High blood pressure in acute stroke: to treat or not to treat (2007)
Journal Article
Sare, G. M., Geeganage, C., & Bath, P. M. (2007). High blood pressure in acute stroke: to treat or not to treat. International Journal of Stroke, 2(3), 172-173. https://doi.org/10.1111/j.1747-4949.2007.00131.x

Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials (2007)
Journal Article
Bath, P. M., & Optimising Analysis of Stroke Trials Collaboration, O. (2007). Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials. Stroke, 38(6), https://doi.org/10.1161/STROKEAHA.106.474080

Background: Most large acute stroke trials have been neutral. Functional outcome is usually analysed using a yes or no answer, e.g. death or dependency vs. independence. We assessed which statistical approaches are most efficient in analysing outcome... Read More about Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials.

Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial (TAIST) (2007)
Journal Article
Sprigg, N., Gray, L. J., Bath, P. M., Lindenstrom, E., Boysen, G., De Deyn, P. P., Friis, P., Leys, D., Marttila, R., Olsson, J.-E., O'Neill, D., & Ringelstein, B. (2007). Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial (TAIST). Journal of the Neurological Sciences, 254(1-2),

Introduction: Baseline severity and clinical stroke syndrome (Oxford Community Stroke Project, OCSP) classification are predictors of outcome in stroke. We used data from the ‘Tinzaparin in Acute Ischaemic Stroke Trial’ (TAIST) to assess the relation... Read More about Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial (TAIST).

Is there a link between aspirin therapy and stroke severity (2007)
Journal Article
Bath, P. M. (2007). Is there a link between aspirin therapy and stroke severity

Published by: http://npg.nature.com/

Colony stimulating factors (blood growth factors) are promising but unproven for treating stroke (2007)
Journal Article
Sprigg, N., & Bath, P. M. (2007). Colony stimulating factors (blood growth factors) are promising but unproven for treating stroke. Stroke, 38,

Effect of nitric oxide donors on blood pressure and pulse pressure in acute and subacute stroke (2006)
Journal Article
Gray, L. J., Sprigg, N., Rashid, P., Willmot, M., & Bath, P. M. (2006). Effect of nitric oxide donors on blood pressure and pulse pressure in acute and subacute stroke. Journal of Stroke and Cerebrovascular Diseases, 15(6),

High blood pressure (BP), pulse pressure (PP), and rate pressure product (RPP) areeach associated independently with a poor outcome in acute ischemic stroke. Whereas nitric oxide (NO) donors, such as glyceryl trinitrate (GTN), lower blood pressure i... Read More about Effect of nitric oxide donors on blood pressure and pulse pressure in acute and subacute stroke.

Control of blood pressure after stroke (2006)
Journal Article
Bath, P. M., & Sprigg, N. (2006). Control of blood pressure after stroke. Hypertension, 48(2),

Significant variation in mortality and functional outcome after acute ischaemic stroke between western countries: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial' (TAIST) (2006)
Journal Article
Gray, L. J., Sprigg, N., Bath, P. M., Sorensen, P., Lindenstrom, E., Boysen, G., …Turpie, A. (2006). Significant variation in mortality and functional outcome after acute ischaemic stroke between western countries: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial' (TAIST). Journal of Neurology, Neurosurgery and Psychiatry, 77,

Effect of aspirin, clopidogrel and dipyridamole on soluble markers of vascular function in normal volunteers and patients with prior ischaemic stroke (2006)
Journal Article
Zhao, L., Gray, L. J., Leonardi-Bee, J., Weaver, C., Heptinstall, S., & Bath, P. M. (2006). Effect of aspirin, clopidogrel and dipyridamole on soluble markers of vascular function in normal volunteers and patients with prior ischaemic stroke. Platelets, 17(2),

Association between hormone replacement therapy and subsequent stroke: a meta analysis (2005)
Journal Article
Bath, P. M., & Gray, L. J. (2005). Association between hormone replacement therapy and subsequent stroke: a meta analysis. British medical journal, 330,

Compression stockings and the prevention of symptomatic venous thromboembolism: data from the Tinzaparin in Acute Ischaemic Stroke Trial (2005)
Journal Article
Sprigg, N., Gray, L. J., Bath, P. M., Boysen, G., de Deyn, P. P., Leys, D., …van der Sande, J. J. (2005). Compression stockings and the prevention of symptomatic venous thromboembolism: data from the Tinzaparin in Acute Ischaemic Stroke Trial. Journal of Stroke and Cerebrovascular Diseases, 14(5),

Background: Venous thromboembolism (VTE) is a well recognised and preventable complication of acute stroke. While graduated compression stockings reduce the risk of VTE in surgical patients their benefit in acute stroke remains uncertain. Methods: T... Read More about Compression stockings and the prevention of symptomatic venous thromboembolism: data from the Tinzaparin in Acute Ischaemic Stroke Trial.

Nitric oxide synthase inhibitors in experimental stroke and their effects on infarct size and cerebral blood flow: a systematic review (2005)
Journal Article
Willmot, M., Gibson, C. L., Gray, L. J., Murphy, S., & Bath, P. M. (2005). Nitric oxide synthase inhibitors in experimental stroke and their effects on infarct size and cerebral blood flow: a systematic review. Free Radical Biology and Medicine, 39,

A systematic review of nitric oxide donors and L-arginine in experimental stroke: effects on infarct size and cerebral blood flow (2005)
Journal Article
Willmot, M., Gray, L. J., Gibson, C. L., Murphy, S., & Bath, P. M. (2005). A systematic review of nitric oxide donors and L-arginine in experimental stroke: effects on infarct size and cerebral blood flow. Nitric Oxide: Biology and Chemistry, 12(3),

Background: Nitric oxide (NO) is a candidate treatment for acute ischaemic stroke, however published studies in experimental stroke have given conflicting results. Methods: We performed a systematic review of published controlled studies of L-arginin... Read More about A systematic review of nitric oxide donors and L-arginine in experimental stroke: effects on infarct size and cerebral blood flow.