Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy
(2017)
Journal Article
Khera, T., Todt, D., Vercauteren, K., McClure, C. P., Verhoye, L., Farhoudi, A., …Brown, R. J. (in press). Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy. Antiviral Research, 139, https://doi.org/10.1016/j.antiviral.2017.01.001
Due to the highly restricted species-tropism of Hepatitis C virus (HCV) a limited number of animal models exist for pre-clinical evaluation of vaccines and antiviral compounds. The human-liver chimeric mouse model allows heterologous challenge with c... Read More about Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy.