All Outputs (2)

Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity (2017)
Journal Article
Paschalis, V., Le Chatelier, E., Green, M., Képès, F., Soultanas, P., & Janniere, L. (2017). Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity. Open Biology, 7(9), Article 170146. https://doi.org/10.1098/rsob.170146

During Bacillus subtilis replication two replicative polymerases function at the replisome to collectively carry out genome replication. In a reconstituted in vitro replication assay, PolC is the main polymerase while the lagging strand DnaE polymera... Read More about Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity.

DNA binding and unwinding by Hel308 helicase requires dual functions of a winged helix domain (2017)
Journal Article
Northall, S. J., Buckley, R., Jones, N., Penedo, J. C., Soultanas, P., & Bolt, E. L. (2017). DNA binding and unwinding by Hel308 helicase requires dual functions of a winged helix domain. DNA Repair, 57, https://doi.org/10.1016/j.dnarep.2017.07.005

Hel308 helicases promote genome stability linked to DNA replication in archaea, and have homologues in metazoans. In the crystal structure of archaeal Hel308 bound to a tailed DNA duplex, core helicase domains encircle single-stranded DNA (ssDNA) in... Read More about DNA binding and unwinding by Hel308 helicase requires dual functions of a winged helix domain.