Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis

Webb, Karmel; Zain, Nur Masirah M.; Stewart, Iain; Fogarty, Andrew; Nash, Edward F.; Whitehouse, Joanna L.; Smyth, Alan R.; Lilley, Andrew K.; Knox, Alan; Williams, Paul; Cámara, Miguel; Bruce, Kenneth; Barr, Helen L.

doi:10.1099/jmm.0.001481

All Outputs (5)

Supporting the strategic pillars of translational research in biofilms (2022)
Journal Article

It is now widely accepted that most microorganisms live within communities and not as single cells. The interaction between species within the community drives the behaviour of the population and its adaptation to various ecosystems and hosts. This r... Read More about Supporting the strategic pillars of translational research in biofilms.

ToxR is a c-di-GMP binding protein that modulates surface-associated behaviour in Pseudomonas aeruginosa (2022)
Journal Article

Pseudomonas aeruginosa uses multiple protein regulators that work in tandem to control the production of a wide range of virulence factors and facilitate rapid adaptation to diverse environmental conditions. In this opportunistic pathogen, ToxR was k... Read More about ToxR is a c-di-GMP binding protein that modulates surface-associated behaviour in Pseudomonas aeruginosa.

Symbiopectobacterium purcellii, gen. nov., sp. nov., isolated from the leafhopper Empoasca decipiens (2022)
Journal Article

Bacterial endosymbionts are found in multiple arthropod species, where they play crucial roles as nutritional symbionts, defensive symbionts or reproductive parasites. Recent work has highlighted a new clade of heritable microbes within the gammaprot... Read More about Symbiopectobacterium purcellii, gen. nov., sp. nov., isolated from the leafhopper Empoasca decipiens.

Economic significance of biofilms: a multidisciplinary and cross-sectoral challenge (2022)
Journal Article

The increasing awareness of the significance of microbial biofilms across different sectors is continuously revealing new areas of opportunity in the development of innovative technologies in translational research, which can address their detrimenta... Read More about Economic significance of biofilms: a multidisciplinary and cross-sectoral challenge.

Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis (2022)
Journal Article

Although anaerobic bacteria exist in abundance in cystic fibrosis (CF) airways, their role in disease progression is poorly understood. We hypothesized that the presence and relative abundance of the most prevalent, live, anaerobic bacteria in sputum... Read More about Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis.