A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial)

Patel, Shireen; Boutry, Clement; Patel, Priya; Craven, Michael P.; Guo, Boliang; Zafar, Azhar; Kai, Joe; Smart, David; Butler, Debbie; Higton, Fred; McNaughton, Rebecca; Briley, Paul M.; Griffiths, Chris; Nixon, Neil; Sayal, Kapil; Morriss, Richard

doi:10.1186/s13063-022-06192-1

Evaluation of technologies and products for psychosocial intervention and support for and with people living with dementia (2024)
Book Chapter

This chapter covers various techniques and methods used to evaluate designs produced collaboratively in the ‘Designing for people with Dementia’ (MinD) programme (MinD, 2023). It extends these by consideration of a broader set of tools for formative... Read More about Evaluation of technologies and products for psychosocial intervention and support for and with people living with dementia.

Usability of web-based tools designed for communication and decision-making in dementia: systematic review and design brief (2024)
Journal Article

Introduction: There is an increased number of web-based tools designed for people with dementia and their family caregivers and addressing communication and decision-making. The loss of cognitive functions associated with dementia can impact individu... Read More about Usability of web-based tools designed for communication and decision-making in dementia: systematic review and design brief.

EmpRess: an eHealth implementation readiness checklist for dementia developed through an interview study of stakeholder needs (2024)
Journal Article

Objective This study aimed to create a tool to assess eHealth interventions for dementia by adapting an existing implementation readiness (ImpRess) checklist that assessed manualised interventions. Methods In Part 1, online semi-structured inter... Read More about EmpRess: an eHealth implementation readiness checklist for dementia developed through an interview study of stakeholder needs.

Adaptative computerized cognitive training decreases mental workload during working memory precision task - A preliminary fNIRS study (2024)
Journal Article

With the growing concern for the health of ageing populations, much research continues to look at the impact of cognitive training, particularly in relation to cognitive decline. We sought to use novel techniques, including augmented reality and port... Read More about Adaptative computerized cognitive training decreases mental workload during working memory precision task - A preliminary fNIRS study.

Virtual, augmented, mixed, and extended reality interventions in healthcare: a systematic review of health economic evaluations and cost-effectiveness (2023)
Journal Article

Introduction Health economic evaluations are required to best understand the value of interventions to the health economy. As extended reality technologies (an umbrella term including virtual, augmented, and mixed reality) become cheaper and more... Read More about Virtual, augmented, mixed, and extended reality interventions in healthcare: a systematic review of health economic evaluations and cost-effectiveness.

Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist (2023)
Presentation / Conference

Situation: eHealth interventions are a possible solution for rising dementia care costs and potential negative effects on carers Problem: Few evidence-based eHealth interventions are implemented in practice Solution : Adapt existing implementa... Read More about Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist.

Developing a prototype digital risk mitigation pathway for children and young people admitted to acute paediatric NHS care in mental health crisis: Protocol of the Safety Assessment in Paediatric healthcare Environments (SAPhE) pathway study (2023)
Journal Article

Background: Globally, there are increasing numbers of Children and young people (CYPs) experiencing a mental health crisis requiring admission to acute paediatric inpatient care. These CYPs can often experience fluctuating emotional states accompanie... Read More about Developing a prototype digital risk mitigation pathway for children and young people admitted to acute paediatric NHS care in mental health crisis: Protocol of the Safety Assessment in Paediatric healthcare Environments (SAPhE) pathway study.

Experiencing the digital working transition in participant and public involvement in dementia research during the COVID‐19 pandemic (2023)
Journal Article

Background Involvement of patients and public in research have been disrupted by the consequences of the COVID-19 pandemic, forcing a rapid transition from face-to-face meetings to digital working as an alternative to engage experts by experience. T... Read More about Experiencing the digital working transition in participant and public involvement in dementia research during the COVID‐19 pandemic.

Clinical Perspectives on Using Remote Measurement Technology in Assessing Epilepsy, Multiple Sclerosis, and Depression: Delphi Study (2023)
Journal Article

Background: Multiple sclerosis (MS), epilepsy, and depression are chronic central nervous system conditions in which remote measurement technology (RMT) may offer benefits compared with usual assessment. We previously worked with clinicians, patients... Read More about Clinical Perspectives on Using Remote Measurement Technology in Assessing Epilepsy, Multiple Sclerosis, and Depression: Delphi Study.

Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol (2023)
Presentation / Conference

Introduction: Traumatic brain injury (TBI) is the most common acquired brain injury (ABI), where 16% of children sustain at least one TBI requiring medical attention, and 25-30% experience chronic problems. Attention and concentration problems are am... Read More about Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol.

Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial (2023)
Journal Article

Background: Randomised sham-controlled trials of cranial electrostimulation with the Alpha-Stim Anxiety Insomnia and Depression (AID) device have reported improved anxiety and depression symptoms; however, no adequately powered sham-controlled trials... Read More about Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial.

Use and uptake of technology by people with dementia and their supporters during the COVID-19 pandemic (2023)
Journal Article

Objective This rapid review aims to identify the types of technologies used by people with dementia and their supporters during the COVID-19 pandemic, and the issues which influenced technology adoption within their usual care routines. Methods... Read More about Use and uptake of technology by people with dementia and their supporters during the COVID-19 pandemic.

Estimating the Economic Value of Automated Virtual Reality Cognitive Therapy for Treating Agoraphobic Avoidance in Patients With Psychosis: Findings From the gameChange Randomized Controlled Clinical Trial (2022)
Journal Article

BACKGROUND: An automated virtual reality cognitive therapy (gameChange) has demonstrated its effectiveness to treat agoraphobia in patients with psychosis, especially for high or severe anxious avoidance. Its economic value to the health care system... Read More about Estimating the Economic Value of Automated Virtual Reality Cognitive Therapy for Treating Agoraphobic Avoidance in Patients With Psychosis: Findings From the gameChange Randomized Controlled Clinical Trial.

Design decisions and data completeness for experience sampling methods used in psychosis: systematic review (2022)
Journal Article

Background: The experience sampling method (ESM) is an intensive longitudinal research method. Participants complete questionnaires at multiple times about their current or very recent state. The design of ESM studies is complex. People with psychosi... Read More about Design decisions and data completeness for experience sampling methods used in psychosis: systematic review.

Insights on conducting digital patient and public involvement in dementia research during the COVID-19 pandemic: supporting the development of an “E-nabling digital co-production” framework (2022)
Journal Article

Background The rapid transition to digital working, accelerated due to the response to the COVID-19 pandemic, has impacted the involvement of patients and public in research. This paper presents experiences of engaging in digital Patient and Public... Read More about Insights on conducting digital patient and public involvement in dementia research during the COVID-19 pandemic: supporting the development of an “E-nabling digital co-production” framework.

Perceptions of Cognitive Training Games and Assessment Technologies for Dementia: Acceptability Study with Patient and Public Involvement Workshops (2022)
Journal Article

Background: Cognitive training and assessment technologies offer the promise of dementia risk reduction and a more timely diagnosis of dementia, respectively. Cognitive training games may help reduce the lifetime risk of dementia by helping to build... Read More about Perceptions of Cognitive Training Games and Assessment Technologies for Dementia: Acceptability Study with Patient and Public Involvement Workshops.

Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals (2022)
Journal Article

BACKGROUND: Epilepsy, multiple sclerosis(MS) and depression are long term, central nervous system disorders which have a significant impact on everyday life. Evaluating symptoms of these conditions is problematic and typically involves repeated visit... Read More about Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals.

A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment (2022)
Journal Article

Objectives: Digital health interventions enable services to support people living with dementia and Mild Cognitive Impairment (MCI) remotely. This literature review gathers evidence on the effectiveness of digital health interventions on physical, co... Read More about A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment.

Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis (gameChange): a multicentre, parallel-group, single-blind, randomised, controlled trial in England with mediation and moderation analyses (2022)
Journal Article

Background Automated delivery of psychological therapy using immersive technologies such as virtual reality (VR) might greatly increase the availability of effective help for patients. We aimed to evaluate the efficacy of an automated VR cognitive t... Read More about Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis (gameChange): a multicentre, parallel-group, single-blind, randomised, controlled trial in England with mediation and moderation analyses.

A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial) (2022)
Journal Article

Background: Major depression is the second leading cause of years lost to disability worldwide and is a leading contributor to suicide. However, first-line antidepressants are only fully effective for 33%, and only 40% of those offered psychological... Read More about A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial).

All Outputs (112)