All Outputs (3)

Low-field, benchtop NMR spectroscopy as a potential tool for point-of-care diagnostics of metabolic conditions: Validation, protocols and computational models (2018)
Journal Article
Percival, B. C., Grootveld, M., Gibson, M., Osman, Y., Molinari, M., Jafari, F., Sahota, T., Martin, M., Casanova, F., Mather, M. L., Edgar, M., Masania, J., & Wilson, P. B. (2019). Low-field, benchtop NMR spectroscopy as a potential tool for point-of-care diagnostics of metabolic conditions: Validation, protocols and computational models. High-Throughput, 8(1), Article 2. https://doi.org/10.3390/ht8010002

Novel sensing technologies for liquid biopsies offer promising prospects for the early detection of metabolic conditions through omics techniques. Indeed, high-field nuclear magnetic resonance (NMR) facilities are routinely used for metabolomics inve... Read More about Low-field, benchtop NMR spectroscopy as a potential tool for point-of-care diagnostics of metabolic conditions: Validation, protocols and computational models.

Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media (2018)
Journal Article
Ahmad, J., Jayet, B., Hill, P. J., Mather, M. L., Dehghani, H., & Morgan, S. P. (in press). Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media. Biomedical Optics Express, 9(4), https://doi.org/10.1364/BOE.9.001664

In vivo imaging of self-illuminating bio-and chemiluminescent reporters is used to observe the physiology of small animals. However, strong light scattering by biological tissues results in poor spatial resolution of the optical imaging, which also d... Read More about Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media.

Label-free, high resolution, multi-modal light microscopy for discrimination of live stem cell differentiation status (2018)
Journal Article
Zhang, J., Moradi, E., Somekh, M. G., & Mather, M. L. (2018). Label-free, high resolution, multi-modal light microscopy for discrimination of live stem cell differentiation status. Scientific Reports, 8(1), Article 697. https://doi.org/10.1038/s41598-017-18714-y

A label-free microscopy method for assessing the differentiation status of stem cells is presented with potential application for characterization of therapeutic stem cell populations. The microscopy system is capable of characterizing live cells bas... Read More about Label-free, high resolution, multi-modal light microscopy for discrimination of live stem cell differentiation status.