Chronic constipation in adults: Contemporary perspectives and clinical challenges. 2: Conservative, behavioural, medical and surgical treatment

Corsetti, Maura; Brown, Steven; Chiarioni, Giuseppe; Dimidi, Eirini; Dudding, Thomas; Emmanuel, Anton; Fox, Mark; Ford, Alexander C.; Giordano, Pasquale; Grossi, Ugo; Henderson, Michelle; Knowles, Charles H.; O�Connell, P. Ronan; Quigley, Eamonn M.M.; Simren, Magnus; Spiller, Robin; Whelan, Kevin; Whitehead, William E.; Williams, Andrew B.; Scott, S. Mark

doi:10.1111/nmo.14070

All Outputs (9)

The tapestry of reflux syndromes: translating new insight into clinical practice (2021)
Journal Article

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia (2021)
Journal Article

Background Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite of its prevalence, FD is associated with major uncertainties in terms of its definition, underlying pathophysiology, diagnosis, treatment, and p... Read More about United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia.

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on Functional Dyspepsia (2021)
Journal Article

Background Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite of its prevalence, FD is associated with major uncertainties in terms of its definition, underlying pathophysiology, diagnosis, treatment, and... Read More about United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on Functional Dyspepsia.

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome (2021)
Journal Article

Irritable bowel syndrome (IBS) remains one of the most common gastrointestinal disorders seen by clinicians in both primary and secondary care. Since publication of the last British Society of Gastroenterology guideline in 2007, substantial advances... Read More about British Society of Gastroenterology guidelines on the management of irritable bowel syndrome.

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis (2021)
Journal Article

Background: Gastroparesis is a condition characterized by epigastric symptoms and delayed gastric emptying (GE) rate in the absence of any mechanical obstruction. The condition is challenging in clinical practice by the lack of guidance concerning... Read More about United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis.

The placebo response rate in pharmacological trials in patients with irritable bowel syndrome: a systematic review and meta-analysis (2021)
Journal Article

Background Clinical trials in irritable bowel syndrome are associated with high placebo response rates. We aimed to identify the magnitude of the placebo response and the contributing factors to this occurrence. Methods We did a systematic revie... Read More about The placebo response rate in pharmacological trials in patients with irritable bowel syndrome: a systematic review and meta-analysis.

Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review (2021)
Journal Article

The absorption of oral drugs is frequently plagued by significant variability with potentially serious therapeutic consequences. The source of variability can be traced back to interindividual variability in physiology, differences in special populat... Read More about Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review.

Bisacodyl: A review of pharmacology and clinical evidence to guide use in clinical practice in patients with constipation (2021)
Journal Article

Background: Bisacodyl is a member of the diphenylmethane family and is considered to be a stimulant laxative. It has a dual prokinetic and secretory action and needs to be converted into the active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (... Read More about Bisacodyl: A review of pharmacology and clinical evidence to guide use in clinical practice in patients with constipation.

Chronic constipation in adults: Contemporary perspectives and clinical challenges. 2: Conservative, behavioural, medical and surgical treatment (2021)
Journal Article

Background: Chronic constipation is a prevalent disorder that affects quality of life of patients and consumes resources in healthcare systems worldwide. In clinical practice, it is still considered a challenge as clinicians frequently are unsure as... Read More about Chronic constipation in adults: Contemporary perspectives and clinical challenges. 2: Conservative, behavioural, medical and surgical treatment.