Detection and Quantification of Novel C?terminal TDP?43 Fragments in ALS?TDP
(2021)
Journal Article
Feneberg, E., Charles, P. D., Finelli, M. J., Scott, C., Kessler, B. M., Fischer, R., …Turner, M. R. (2021). Detection and Quantification of Novel C‐terminal TDP‐43 Fragments in ALS‐TDP. Brain Pathology, 31(4), Article e12923. https://doi.org/10.1111/bpa.12923
The pathological hallmark of amyotrophic lateral sclerosis (ALS) is the presence of cytoplasmic inclusions, containing C‐terminal fragments of the protein TDP‐43. Here, we tested the hypothesis that highly sensitive mass spectrometry with parallel re... Read More about Detection and Quantification of Novel C?terminal TDP?43 Fragments in ALS?TDP.