Fluorescent nanosensors reveal dynamic pH gradients during biofilm formation

Hollmann, Birte; Perkins, Mark; Chauhan, Veeren M.; Aylott, Jonathan W.; Hardie, Kim R.

doi:10.1038/s41522-021-00221-8

All Outputs (3)

JMM Profile: Carbapenems: a broad-spectrum antibiotic (2021)
Journal Article

Carbapenems are potent members of the β-lactam family that inhibit bacterial cell-wall biosynthesis inhibitors . They are highly effective against Gram-negative and Gram-positive drug-resistant infections . As such, carbapenems are typically reserved... Read More about JMM Profile: Carbapenems: a broad-spectrum antibiotic.

Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through lack of the Rieske cytochrome bc1sub-unit (2021)
Journal Article

Extracellular DNA (eDNA) is a major constituent of the extracellular matrix of Pseudomonas aeruginosa biofilms and its release is regulated via pseudomonas quinolone signal (PQS) dependent quorum sensing (QS). By screening a P. aeruginosa transposon... Read More about Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through lack of the Rieske cytochrome bc1sub-unit.

Fluorescent nanosensors reveal dynamic pH gradients during biofilm formation (2021)
Journal Article

Understanding the dynamic environmental microniches of biofilms will permit us to detect, manage and exploit these communities. The components and architecture of biofilms have been interrogated in depth; however, little is known about the environmen... Read More about Fluorescent nanosensors reveal dynamic pH gradients during biofilm formation.