All Outputs (5)

Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin (2021)
Journal Article
Al-Beltagi, S., Goulding, L. V., Chang, D. K., Mellits, K. H., Hayes, C. J., Gershkovich, P., …Chang, K. (2021). Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin. Virulence, 12(1), 2946-2956. https://doi.org/10.1080/21505594.2021.2006960

The struggle to control the COVID-19 pandemic is made challenging by the emergence of virulent SARS-CoV-2 variants. To gain insight into their replication dynamics, emergent Alpha (A), Beta (B) and Delta (D) SARS-CoV-2 variants were assessed for thei... Read More about Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin.

Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation (2015)
Journal Article
Chang, P., Kuchipudi, S. V., Mellits, K., Sebastian, S., James, J., Liu, J., …Chang, K. (2015). Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation. Scientific Reports, 5(17999), https://doi.org/10.1038/srep17999

Pigs are evidently more resistant to avian than swine influenza A viruses, mediated in part through frontline epithelial cells and alveolar macrophages (AM). Although porcine AM (PAM) are crucial in influenza virus control, their mode of control is u... Read More about Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation.

Effect of a single dose of Saccharomyces cerevisiae var. boulardii on the occurrence of porcine neonatal diarrhoea (2015)
Journal Article
Hancox, L., Le Bon, M., Richards, P., Guillou, D., Dodd, C. E., & Mellits, K. (in press). Effect of a single dose of Saccharomyces cerevisiae var. boulardii on the occurrence of porcine neonatal diarrhoea. animal, 9(11), https://doi.org/10.1017/S1751731114002687

Piglet neonatal diarrhoea is an important issue in modern pig production and is linked to increased mortality and poor growth rates, affecting long-term pig health, increasing use of medication and cost of production. Saccharomyces cerevisiae var. bo... Read More about Effect of a single dose of Saccharomyces cerevisiae var. boulardii on the occurrence of porcine neonatal diarrhoea.

Assessment of caecal parameters in layer hens fed on diets containing wheat distillers dried grains with solubles (2015)
Journal Article
White, G. A., Richards, P. J., Wu, S., Mellits, K. H., & Wiseman, J. (2015). Assessment of caecal parameters in layer hens fed on diets containing wheat distillers dried grains with solubles. British Poultry Science, 56(4), 494-502. https://doi.org/10.1080/00071668.2015.1064859

There is much interest in quantifying the nutritional value of UK wheat distillers dried grains with solubles (W-DDGS) for livestock species. A study was designed to evaluate caecal parameters (pH, short chain fatty acids (SCFAs) and bacterial divers... Read More about Assessment of caecal parameters in layer hens fed on diets containing wheat distillers dried grains with solubles.

Inclusion of detergent in a cleaning regime and effect on microbial load in livestock housing (2013)
Journal Article
Hancox, L., Le Bon, M., Dodd, C. E., & Mellits, K. (2013). Inclusion of detergent in a cleaning regime and effect on microbial load in livestock housing. Veterinary Record, 173(7), https://doi.org/10.1136/vr.101392

Determining effective cleaning and disinfection regimes of livestock housing is vital to improving the health of resident animals and reducing zoonotic disease. A cleaning regime consisting of scraping, soaking with or without detergent (treatment an... Read More about Inclusion of detergent in a cleaning regime and effect on microbial load in livestock housing.