Synthesis of ?-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2

Roy, Rana; Usha, Veeraraghavan; Kermani, Ali; Scott, David J.; Hyde, Eva I.; Besra, Gurdyal S.; Alderwick, Luke J.; F�tterer, Klaus

doi:10.1021/cb400508k

All Outputs (3)

Unbiased analysis of the impact of micropatterned biomaterials on macrophage behaviour provides insights beyond pre-defined polarisation states (2017)
Journal Article

Macrophages are master regulators of immune responses towards implanted biomaterials. The activation state adopted by macrophages in response to biomaterials determines their own phenotype and function as well as those of other resident and infiltrat... Read More about Unbiased analysis of the impact of micropatterned biomaterials on macrophage behaviour provides insights beyond pre-defined polarisation states.

A paper-based in vitro model for on-chip investigation of the human respiratory system (2016)
Journal Article

Culturing cells at the air–liquid interface (ALI) is essential for creating functional in vitro models of lung tissues. We present the use of direct-patterned laser-treated hydrophobic paper as an effective semi-permeable membrane, ideal for ALI cell... Read More about A paper-based in vitro model for on-chip investigation of the human respiratory system.

Synthesis of ?-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2 (2013)
Journal Article

Recent evidence established that the cell envelope of Mycobacterium tuberculosis, the bacillus causing tuberculosis (TB), is coated by an ?-glucan-containing capsule that has been implicated in persistence in a mouse infection model. As one of three... Read More about Synthesis of ?-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2.