Core Outcome Domains for early phase clinical trials of sound-, psychology-, and pharmacology-based interventions to manage chronic subjective tinnitus in adults: The COMIT'ID study protocol for using a Delphi process and face-to-face meetings to establish consensus

Fackrell, Kathryn; Smith, Harriet; Colley, Veronica; Thacker, Brian; Horobin, Adele Jayne; Haider, Haula; Londero, Alain; Mazurek, Birgit; Hall, Deborah A.

doi:10.1186/s13063-017-2123-0

All Outputs (4)

Performance of the Tinnitus Functional Index as a diagnostic instrument in a UK clinical population (2017)
Journal Article

Objectives: The Tinnitus Functional Index (TFI) has been optimised as a diagnostic tool for quantifying the functional impact of tinnitus in US veteran and civilian groups. However, the TFI has not been evaluated for use in other English-speaking cl... Read More about Performance of the Tinnitus Functional Index as a diagnostic instrument in a UK clinical population.

Clinical interventions for hyperacusis in adults: a scoping review to assess the current position and determine priorities for research (2017)
Journal Article

Background. There is no universally accepted definition for hyperacusis, but in general it is characterised by decreased sound tolerance to ordinary environmental sounds. Despite hyperacusis being prevalent and having significant clinical implication... Read More about Clinical interventions for hyperacusis in adults: a scoping review to assess the current position and determine priorities for research.

How to choose between measures of tinnitus loudness for clinical research?: a report on the reliability and validity of an investigator-administered test and a patient-reported measure using baseline data collected in a phase IIa drug trial (2017)
Journal Article

Purpose: Loudness is a major auditory dimension of tinnitus, and is used to diagnose severity, counsel patients or as a measure of clinical efficacy in audiological research. There is no standard test for tinnitus loudness, but matching and rating me... Read More about How to choose between measures of tinnitus loudness for clinical research?: a report on the reliability and validity of an investigator-administered test and a patient-reported measure using baseline data collected in a phase IIa drug trial.

Core Outcome Domains for early phase clinical trials of sound-, psychology-, and pharmacology-based interventions to manage chronic subjective tinnitus in adults: The COMIT'ID study protocol for using a Delphi process and face-to-face meetings to establish consensus (2017)
Journal Article

© 2017 The Author(s). Background: The reporting of outcomes in clinical trials of subjective tinnitus indicates that many different tinnitus-related complaints are of interest to investigators, from perceptual attributes of the sound (e.g. loudness)... Read More about Core Outcome Domains for early phase clinical trials of sound-, psychology-, and pharmacology-based interventions to manage chronic subjective tinnitus in adults: The COMIT'ID study protocol for using a Delphi process and face-to-face meetings to establish consensus.