Performance evaluation of a non-invasive one-step multiplex RT-qPCR assay for detection of SARS-CoV-2 direct from saliva

Jenkins, Harry H; Lopez, Ana A Tellechea; Tarantini, Francesco Saverio; Tomlin, Hannah; Scales, Danielle; Lee, I-Ning; Wu, Siyu; Hyde, Ralph; Lis-Slimak, Katarzyna; Byaruhanga, Timothy; Thompson, Jamie L; Pijuan-Galito, Sara; Doolan, Lara; Kaneko, Kazuyo; Gwynne, Penny; Reffin, Caroline; Park, Emily; Dey, Jayasree; Hill, Jack; Arendt-Tranholm, Asta; Stroud, Amy; Petrie, Moira; Denning, Chris; Benest, Andrew V; Seedhouse, Claire

doi:10.1038/s41598-022-15616-6

All Outputs (2)

OptoRheo: Simultaneous in situ micro-mechanical sensing and imaging of live 3D biological systems (2023)
Journal Article
Mendonca, T., Lis-Slimak, K., Matheson, A. B., Smith, M. G., Anane-Adjei, A. B., Ashworth, J. C., …Wright, A. J. (2023). OptoRheo: Simultaneous in situ micro-mechanical sensing and imaging of live 3D biological systems. Communications Biology, 6, Article 463. https://doi.org/10.1038/s42003-023-04780-8

Biomechanical cues from the extracellular matrix (ECM) are essential for directing many cellular processes, from normal development and repair, to disease progression. To better understand cell-matrix interactions, we have developed a new instrument... Read More about OptoRheo: Simultaneous in situ micro-mechanical sensing and imaging of live 3D biological systems.

Performance evaluation of a non-invasive one-step multiplex RT-qPCR assay for detection of SARS-CoV-2 direct from saliva (2022)
Journal Article
Jenkins, H. H., Lopez, A. A. T., Tarantini, F. S., Tomlin, H., Scales, D., Lee, I., …Seedhouse, C. (2022). Performance evaluation of a non-invasive one-step multiplex RT-qPCR assay for detection of SARS-CoV-2 direct from saliva. Scientific Reports, 12(1), Article 11553. https://doi.org/10.1038/s41598-022-15616-6

Polymerase chain reaction (PCR) has proven to be the gold-standard for SARS-CoV-2 detection in clinical settings. The most common approaches rely on nasopharyngeal specimens obtained from swabs, followed by RNA extraction, reverse transcription and q... Read More about Performance evaluation of a non-invasive one-step multiplex RT-qPCR assay for detection of SARS-CoV-2 direct from saliva.