Increases in intracellular calcium perturb blood–brain barrier via protein kinase C-alpha and apoptosis

Rakkar, Kamini; Bayraktutan, Ulvi

doi:10.1016/j.bbadis.2015.10.016

All Outputs (2)

Inhibition of TNF-? protects in vitro brain barrier from ischaemic damage (2015)
Journal Article

Cerebral ischaemia, associated with neuroinflammation and oxidative stress, is known to perturb blood–brain barrier (BBB) integrity and promote brain oedema formation. Using an in vitro model of human BBB composed of brain microvascular endothelial c... Read More about Inhibition of TNF-? protects in vitro brain barrier from ischaemic damage.

Increases in intracellular calcium perturb blood–brain barrier via protein kinase C-alpha and apoptosis (2015)
Journal Article

An increase in intracellular calcium represents one of the early events during an ischaemic stroke. It triggers many downstream processes which promote the formation of brain oedema, the leading cause of death after an ischaemic stroke. As impairment... Read More about Increases in intracellular calcium perturb blood–brain barrier via protein kinase C-alpha and apoptosis.