Activated tissue resident memory T-cells (CD8+CD103+CD39+) uniquely predict survival in left sided “immune-hot” colorectal cancers

Talhouni, Shahd; Fadhil, Wakkas; Mongan, Nigel P.; Field, Lara; Hunter, Kelly; Makhsous, Sogand; Maciel-Guerra, Alexandre; Kaur, Nayandeep; Nestarenkaite, Ausrine; Laurinavicius, Arvydas; Willcox, Benjamin E.; Dottorini, Tania; Spendlove, Ian; Jackson, Andrew M.; Ilyas, Mohammad; Ramage, Judith M.

doi:10.3389/fimmu.2023.1057292

All Outputs (2)

Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma. (2023)
Journal Article

Ependymoma (EPN) is a devastating childhood brain tumor. Single-cell analyses have illustrated the cellular heterogeneity of EPN tumors, identifying multiple neoplastic cell states including a mesenchymal-differentiated subpopulation which characteri... Read More about Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma..

Activated tissue resident memory T-cells (CD8+CD103+CD39+) uniquely predict survival in left sided “immune-hot” colorectal cancers (2023)
Journal Article

Introduction: Characterization of the tumour immune infiltrate (notably CD8+ T-cells) has strong predictive survival value for cancer patients. Quantification of CD8 T-cells alone cannot determine antigenic experience, as not all infiltrating T-cells... Read More about Activated tissue resident memory T-cells (CD8+CD103+CD39+) uniquely predict survival in left sided “immune-hot” colorectal cancers.