Asymmetric reduction of ?, ?-unsaturated ketone to (R) allylic alcohol by Candida chilensis
(2006)
Journal Article
Pollard, D. J., Telari, K., Lane, J., Humphrey, G., McWilliams, C., Nidositko, S., …Moore, J. (2006). Asymmetric reduction of α, β-unsaturated ketone to (R) allylic alcohol by Candida chilensis. Biotechnology and Bioengineering, 93(4), 674-686. https://doi.org/10.1002/bit.20751
A pilot scale whole cell process was developed for the enantioselective 1,2‐reduction of prochiral α,β‐unsaturated ketone to (R) allylic alcohol using Candida chilensis. Initial development showed high enantiomeric excess (EE > 95%) but low product y... Read More about Asymmetric reduction of ?, ?-unsaturated ketone to (R) allylic alcohol by Candida chilensis.