Formation of a Copper(II)–Tyrosyl Complex at the Active Site of Lytic Polysaccharide Monooxygenases Following Oxidation by H2O2

Paradisi, Alessandro; Johnston, Esther M.; Tovborg, Morten; Nicoll, Callum R.; Ciano, Luisa; Dowle, Adam; McMaster, Jonathan; Hancock, Y.; Davies, Gideon J.; Walton, Paul H.

doi:10.1021/jacs.9b09833

All Outputs (2)

Imidazolylidene Cu(II) complexes: synthesis using imidazolium carboxylate precursors and structure rearrangement pathways (2019)
Journal Article

Copper(II) complexes of type (NHC)CuX2 (X = OAc, Cl, Br, BF4, NO3) bearing monodentate N-heterocyclic carbenes (NHCs) were prepared by in situ decarboxylation of imidazolium carboxylates as a new synthetic methodology for Cu(II)-NHC complexes. In con... Read More about Imidazolylidene Cu(II) complexes: synthesis using imidazolium carboxylate precursors and structure rearrangement pathways.

Formation of a Copper(II)–Tyrosyl Complex at the Active Site of Lytic Polysaccharide Monooxygenases Following Oxidation by H2O2 (2019)
Journal Article

Hydrogen peroxide is a cosubstrate for the oxidative cleavage of saccharidic substrates by copper-containing lytic polysaccharide monooxygenases (LPMOs). The rate of reaction of LPMOs with hydrogen peroxide is high, but it is accompanied by rapid in... Read More about Formation of a Copper(II)–Tyrosyl Complex at the Active Site of Lytic Polysaccharide Monooxygenases Following Oxidation by H2O2.