Crystal structure and substrate-induced activation of ADAMTS13
(2019)
Journal Article
Platelet recruitment to sites of blood vessel damage is highly dependent upon von Willebrand factor (VWF). VWF platelet-tethering function is proteolytically regulated by the metalloprotease ADAMTS13. Proteolysis depends upon shear-induced conformati... Read More about Crystal structure and substrate-induced activation of ADAMTS13.