The selectivity of α‐adrenoceptor agonists for the human α1A, α1B, and α1D‐adrenoceptors
(2021)
Journal Article
Proudman, R. G. W., & Baker, J. G. (2021). The selectivity of α‐adrenoceptor agonists for the human α1A, α1B, and α1D‐adrenoceptors. Pharmacology Research and Perspectives, 9(4), Article e00799. https://doi.org/10.1002/prp2.799
Highly selective drugs offer a way to minimize side-effects. For agonist ligands, this could be through highly selective affinity or highly selective efficacy, but this requires careful measurements of intrinsic efficacy. The α1-adrenoceptors are imp... Read More about The selectivity of α‐adrenoceptor agonists for the human α1A, α1B, and α1D‐adrenoceptors.