Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines
(2024)
Journal Article
So, R. B., Li, G., Brentville, V., Daly, J. M., & Dixon, J. E. (2024). Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines. Journal of Controlled Release, 367, 209-222. https://doi.org/10.1016/j.jconrel.2024.01.031
Physical-based gene delivery via biolistic methods (such as the Helios gene gun) involve precipitation of nucleic acids onto microparticles and direct transfection through cell membranes of exposed tissue (e.g. skin) by high velocity acceleration. Th... Read More about Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines.