Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold

Pitrolino, Katherine A.; Felfel, Reda M.; Pellizzeri, Laura Macri; McLaren, Jane; Popov, Alexander A.; Sottile, Virginie; Scotchford, Colin A.; Scammell, Brigitte E.; Roberts, George A.F.; Grant, David M.

doi:10.1016/j.carbpol.2022.119126

All Outputs (2)

RAPID INTRAOPERATIVE GENETIC AUGMENTATION OF AUTOGRAFTS FOR RECONSTRUCTIVE SURGERY OF SEVERE TRAUMA (2022)
Journal Article
Dixon, J., Thi Mai, T., McLaren, J., Ollivere, B., Scammell, B., & Eltaher, H. (2022). RAPID INTRAOPERATIVE GENETIC AUGMENTATION OF AUTOGRAFTS FOR RECONSTRUCTIVE SURGERY OF SEVERE TRAUMA. Tissue Engineering: Parts A, B, and C, 28(S1),

Survivors with severe tissue injury have unmet clinical needs for better bone and soft tissue regeneration. Specifically they have progressive tissue loss due to inflammation, necrosis, infection and the development of critical size bone defects is a... Read More about RAPID INTRAOPERATIVE GENETIC AUGMENTATION OF AUTOGRAFTS FOR RECONSTRUCTIVE SURGERY OF SEVERE TRAUMA.

Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold (2022)
Journal Article
Pitrolino, K. A., Felfel, R. M., Pellizzeri, L. M., McLaren, J., Popov, A. A., Sottile, V., …Grant, D. M. (2022). Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold. Carbohydrate Polymers, 282, Article 119126. https://doi.org/10.1016/j.carbpol.2022.119126

An innovative approach was developed to engineer a multi-layered chitosan scaffold for osteochondral defect repair. A combination of freeze drying and porogen-leaching out methods produced a porous, bioresorbable scaffold with a distinct gradient of... Read More about Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold.