All Outputs (2)

Evidence for selection in a prokaryote pangenome (2020)
Working Paper
Whelan, F. J., Hall, R. J., & McInerney, J. O. Evidence for selection in a prokaryote pangenome

A pangenome is the complete set of genes (core and accessory) present in a phylogenetic clade. We hypothesize that a pangenome’s accessory gene content is structured and maintained by selection. To test this hypothesis, we interrogated the genomes of... Read More about Evidence for selection in a prokaryote pangenome.

Coinfinder: Detecting Significant Associations and Dissociations in Pangenomes (2019)
Working Paper
Whelan, F. J., Rusilowicz, M., & McInerney, J. O. Coinfinder: Detecting Significant Associations and Dissociations in Pangenomes

The accessory genes of prokaryote and eukaryote pangenomes accumulate by horizontal gene transfer, differential gene loss, and the effects of selection and drift. We have developed Coinfinder, a software program that assesses whether sets of homologo... Read More about Coinfinder: Detecting Significant Associations and Dissociations in Pangenomes.