All Outputs (174)

Visual inspection for diagnosing cutaneous melanoma in adults (2018)
Journal Article

Background: Melanoma has one of the fastest rising incidence rates of any cancer. It accounts for a small percentage of skin cancer cases but is responsible for the majority of skin cancer deaths. History-taking and visual inspection of a suspicious... Read More about Visual inspection for diagnosing cutaneous melanoma in adults.

Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults (2018)
Journal Article

© 2018 The Cochrane Collaboration. Background: Early accurate detection of all skin cancer types is important to guide appropriate management, to reduce morbidity and to improve survival. Basal cell carcinoma (BCC) is almost always a localised skin c... Read More about Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults.

Exfoliative cytology for the diagnosis of basal cell carcinoma and other skin cancers in adults (2018)
Journal Article

Background: Early accurate detection of all skin cancer types is essential to guide appropriate management and to reduce morbidity and improve survival. Basal cell carcinoma (BCC) is usually localised to the skin with potential to infiltrate and dama... Read More about Exfoliative cytology for the diagnosis of basal cell carcinoma and other skin cancers in adults.

Teledermatology for the diagnosis of skin cancer in adults (2018)
Journal Article

Background: Early accurate detection of all skin cancer types is essential to guide appropriate management and to improve morbidity and survival. Melanoma and squamous cell carcinoma (SCC) are high risk skin cancers which have the potential to metast... Read More about Teledermatology for the diagnosis of skin cancer in adults.

Dermoscopy, with and without visual inspection, for the diagnosis of melanoma in adults (2018)
Journal Article

Background: Melanoma has one of the fastest rising incidence rates of any cancer. It accounts for a small percentage of skin cancer cases but is responsible for the majority of skin cancer deaths. Although history-taking and visual inspection of a su... Read More about Dermoscopy, with and without visual inspection, for the diagnosis of melanoma in adults.

Smartphone applications for triaging adults with skin lesions that are suspicious for melanoma (2018)
Journal Article

Background: Melanoma accounts for a small proportion of all skin cancer cases but is responsible for the majority of skin cancer-related deaths. Early detection and treatment can improve survival. Smartphone applications are readily accessible and po... Read More about Smartphone applications for triaging adults with skin lesions that are suspicious for melanoma.

Early aggressive intervention for infantile atopic dermatitis to prevent development of food allergy: a multicenter, investigator-blinded, randomized, parallel group controlled trial (PACI Study): protocol for a randomized controlled trial (2018)
Journal Article

Background: Atopic dermatitis is the first clinical manifestation of the atopic march, with the highest incidence in the first year of life. Those affected often go on to develop other allergic diseases including food allergy, asthma, and allergic rh... Read More about Early aggressive intervention for infantile atopic dermatitis to prevent development of food allergy: a multicenter, investigator-blinded, randomized, parallel group controlled trial (PACI Study): protocol for a randomized controlled trial.

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 (2018)
Journal Article

Background: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services... Read More about Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017.

Adding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT (2018)
Journal Article

Plain English Summary Eczema is very common in children and can have a significant impact, causing itching and sleep problems. The main treatments are emollients, which are used to moisturise the skin, and steroid creams or ointments to treat flare-... Read More about Adding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT.

Feasibility of weekly participant‐reported data collection in a pragmatic randomised controlled trial in primary care: experiences from the BATHE trial (Bath Additives for the Treatment of cHildhood Eczema) (2018)
Journal Article

Background: Patient‐reported outcomes measures in clinical trials ensure that evaluations of effectiveness focus on outcomes that are important to patients. In relapsing‐remitting conditions such as eczema, repeated measurements may allow a more accu... Read More about Feasibility of weekly participant‐reported data collection in a pragmatic randomised controlled trial in primary care: experiences from the BATHE trial (Bath Additives for the Treatment of cHildhood Eczema).

Response to Critical appraisal of LIBERTY AD CHRONOS: reply from authors (2018)
Journal Article

Changes in health in the countries of the UK and 150 English Local Authority areas 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 (2018)
Journal Article

Background Previous studies have reported national and regional Global Burden of Disease (GBD) estimates for the UK. Because of substantial variation in health within the UK, action to improve it requires comparable estimates of disease burden and r... Read More about Changes in health in the countries of the UK and 150 English Local Authority areas 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016.

Development of a core outcome set for therapeutic clinical trials enrolling dogs with atopic dermatitis (COSCAD’18) (2018)
Journal Article

Background: For decades, the efficacy of interventions in clinical trials enrolling dogs with atopic dermatitis (AD) relied on heterogeneous evaluations of skin lesions and pruritus using unvalidated tools. Although some instruments for clinical sign... Read More about Development of a core outcome set for therapeutic clinical trials enrolling dogs with atopic dermatitis (COSCAD’18).

The development of a protocol for diagnosing hand dermatitis from photographic images (2018)
Journal Article

Background: A hand photography protocol was needed to ascertain the presence and severity of dermatitis in a trial testing the effectiveness of a behaviour change intervention to prevent hand dermatitis in nurses. Methods: We developed the protocol... Read More about The development of a protocol for diagnosing hand dermatitis from photographic images.

What’s new in psoriasis treatment? An analysis of systematic reviews published in 2015 (2018)
Journal Article

This review provides a summary of key findings from 27 systematic reviews of 51 articles first published or indexed during 2015, focusing on the treatment of psoriasis as well as precision medicine in psoriasis. Evidence supports weight loss interven... Read More about What’s new in psoriasis treatment? An analysis of systematic reviews published in 2015.

Standardized reporting of the Eczema Area and Severity Index (EASI) and the Patient-Oriented Eczema Measure (POEM): a recommendation by the Harmonising Outcome Measures for Eczema (HOME) Initiative (2018)
Journal Article

Emollient bath additives for the treatment of childhood eczema (BATHE): multi-centre pragmatic parallel group randomised controlled trial of clinical and cost-effectiveness (2018)
Journal Article

Objectives: To determine the clinical and cost-effectiveness of including emollient bath additives in the management of childhood eczema. Trial design: Pragmatic randomised open-label superiority trial with two parallel groups. Setting and recrui... Read More about Emollient bath additives for the treatment of childhood eczema (BATHE): multi-centre pragmatic parallel group randomised controlled trial of clinical and cost-effectiveness.

Interventions for preventing occupational irritant hand dermatitis (Review) (2018)
Journal Article

Background: Occupational irritant hand dermatitis (OIHD) causes significant functional impairment, disruption of work, and discomfort in the working population. Different preventive measures such as protective gloves, barrier creams and moisturisers... Read More about Interventions for preventing occupational irritant hand dermatitis (Review).

Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative) (2018)
Journal Article

This is the report from the fifth meeting of the Harmonising Outcome Measures for Eczema initiative (HOME V). The meeting was held on 12–14 June 2017 in Nantes, France, with 81 participants. The main aims of the meeting were (i) to achieve consensus... Read More about Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative).

Home interventions and light therapy for treatment of vitiligo (HI-Light Vitiligo Trial): study protocol for a randomized controlled trial (2018)
Journal Article

Vitiligo is a condition resulting in white patches on the skin. People with vitiligo can suffer from low self-esteem, psychological disturbance and diminished quality of life. Vitiligo is often poorly managed, partly due to lack of high quality evide... Read More about Home interventions and light therapy for treatment of vitiligo (HI-Light Vitiligo Trial): study protocol for a randomized controlled trial.