All Outputs (7)

A clozapine-like effect of cyproheptadine on progressive ratio schedule performance (2011)
Journal Article

The atypical antipsychotic drug clozapine has multiple pharmacological actions, some of which, including 5-hydroxytryptamine (5-HT2) and histamine (H1) receptor antagonist effects, are shared by the non-selective 5-HT receptor antagonist cyproheptadi... Read More about A clozapine-like effect of cyproheptadine on progressive ratio schedule performance.

The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects (2011)
Journal Article

There is good evidence that the medial prefrontal cortex (mPFC) is involved in different aspects of recognition memory. However, the mPFC is a heterogeneous structure, and the contribution of the prelimbic (PL) and infralimbic (IL) cortices to recogn... Read More about The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects.

Catecholaminergic depletion in nucleus accumbens enhances trace conditioning (2011)
Journal Article

Purpose: To examine the effect of dopamine depletion in nucleus accumbens on trace conditioning; to distinguish the role of core and shell sub-regions, as far as possible. Material/Methods: 6-hydroxydopamine was used to lesion dopamine terminals with... Read More about Catecholaminergic depletion in nucleus accumbens enhances trace conditioning.

Reduced dopamine function within the medial shell of the nucleus accumbens enhances latent inhibition (2011)
Journal Article

Latent inhibition (LI) manifests as poorer conditioning to a CS that has previously been presented without consequence. There is some evidence that LI can be potentiated by reduced mesoaccumbal dopamine (DA) function but the locus within the nucleus... Read More about Reduced dopamine function within the medial shell of the nucleus accumbens enhances latent inhibition.

Impaired Pavlovian conditioned inhibition in offenders with personality disorders (2011)
Journal Article

Certain types of violent offending are often accompanied by evidence of personality disorders (PDs), a range of heterogeneous conditions characterised by disinhibited behaviours that are generally described as impulsive. The tasks previously used to... Read More about Impaired Pavlovian conditioned inhibition in offenders with personality disorders.

Associative learning in ADHD: improved expression under methylphenidate (2011)
Journal Article

Attention Deficit/Hyperactivity Disorder (ADHD) is characterised by developmentally inappropriate levels of inattention, impulsivity and hyperactivity. As might be expected of a disorder in which inhibitory deficits form part of the diagnostic criter... Read More about Associative learning in ADHD: improved expression under methylphenidate.

The normal inhibition of associations is impaired by clonidine in Tourette syndrome (2011)
Journal Article

Objective: We examined the inhibition of stimulus-stimulus associations (formally ‘conditioned inhibition’) in Tourette syndrome (TS). Method: The present study used video game style conditioned inhibition procedures suitable for children and adolesc... Read More about The normal inhibition of associations is impaired by clonidine in Tourette syndrome.