Skip to main content

Research Repository

Advanced Search

All Outputs (3)

A comparative, randomised MRI study of the physiological and appetitive responses to gelling (alginate) and non-gelling nasogastric tube feeds in healthy men (2023)
Journal Article
Aliyu, A. I., Nixon, A., Hoad, C., Marciani, L., Corsetti, M., Aithal, G. P., …Taylor, M. A. (2023). A comparative, randomised MRI study of the physiological and appetitive responses to gelling (alginate) and non-gelling nasogastric tube feeds in healthy men. British Journal of Nutrition, 130(8), 1316-1328. https://doi.org/10.1017/S0007114523000302

AbstractInclusion in nasogastric tube feeds (NGTF) of acid-sensitive, seaweed-derived alginate, expected to form a reversible gel in the stomach, may create a more normal intragastric state and modified gastrointestinal responses. This may ameliorate... Read More about A comparative, randomised MRI study of the physiological and appetitive responses to gelling (alginate) and non-gelling nasogastric tube feeds in healthy men.

Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated (2023)
Journal Article
Atallah, E., Grove, J., Crooks, C., Burden-Teh, E., Abhishek, A., Moreea, S., …Aithal, G. (2023). Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated. Journal of Hepatology, 78(5), 989-997. https://doi.org/10.1016/j.jhep.2022.12.034

Background & Aims The risk of significant liver fibrosis from prolonged methotrexate (MTX) exposure has been estimated at around 5%, prompting intensive monitoring strategies. However, the evidence is derived from retrospective studies that under-re... Read More about Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated.

The effect of acute and chronic exercise on hepatic lipid composition (2023)
Journal Article
Willis, S. A., Malaikah, S., Parry, S., Bawden, S., Ennequin, G., Sargeant, J. A., …King, J. A. (2023). The effect of acute and chronic exercise on hepatic lipid composition. Scandinavian Journal of Medicine and Science in Sports, 33(5), 550-568. https://doi.org/10.1111/sms.14310

Exercise is recommended for those with, or at risk of nonalcoholic fatty liver disease (NAFLD), owing to beneficial effects on hepatic steatosis and cardiometabolic risk. Whilst exercise training reduces total intrahepatic lipid in people with NAFLD,... Read More about The effect of acute and chronic exercise on hepatic lipid composition.