All Outputs (2)

Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage (2013)
Journal Article
Sheridan, G. K., & Murphy, K. J. (2013). Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage. Open Biology, 3(12), Article 130181. https://doi.org/10.1098/rsob.130181

An essential aspect of normal brain function is the bidirectional interaction and communication between neurons and neighbouring glial cells. To this end, the brain has evolved ligand-receptor partnerships that facilitate crosstalk between different... Read More about Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage.

Pathway specific modulation of S1P1 receptor signalling in rat and human astrocytes (2013)
Journal Article
Healy, L. M., Sheridan, G. K., Pritchard, A. J., Rutkowska, A., Mullershausen, F., & Dev, K. K. (2013). Pathway specific modulation of S1P1 receptor signalling in rat and human astrocytes. British Journal of Pharmacology, 169(5), 1114-1129. https://doi.org/10.1111/bph.12207

Background and Purpose The sphingosine 1-phosphate receptor subtype 1 (S1P1R) is modulated by phosphorylated FTY720 (pFTY720), which causes S1P1R internalization preventing lymphocyte migration thus limiting autoimmune response. Studies indicate that... Read More about Pathway specific modulation of S1P1 receptor signalling in rat and human astrocytes.