All Outputs (73)

Acetarsol Suppositories: Effective Treatment for Refractory Proctitis in a Cohort of Patients with Inflammatory Bowel Disease (2018)
Journal Article

Background: Management of proctitis refractory to conventional therapies presents a common clinical problem. The use of acetarsol suppositories, which are derived from organic arsenic, was frst described in 1965. Data concerning clinical efficacy and... Read More about Acetarsol Suppositories: Effective Treatment for Refractory Proctitis in a Cohort of Patients with Inflammatory Bowel Disease.

Surgical rates for Crohn’s Disease are decreasing: a population-based time trend analysis and validation study (2017)
Journal Article

Objectives: Temporal changes for intestinal resections for Crohn’s disease (CD) are controversial. We validated administrative database codes for CD diagnosis and surgery in hospitalized patients and then evaluated temporal trends in CD surgical res... Read More about Surgical rates for Crohn’s Disease are decreasing: a population-based time trend analysis and validation study.

MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans (2017)
Journal Article

Background: Feeding triggers inter-related gastrointestinal (GI) motor, peptide and appetite responses. These are rarely studied together due to methodological limitations. Recent MRI advances allow pan-intestinal, non-invasive assessment of motility... Read More about MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans.

Combination of corticosteroids and 5-aminosalicylates or corticosteroids alone for patients with moderate-severe active ulcerative colitis: A global survey of physicians' practice (2017)
Journal Article

The Pattern of Underlying Cause of Death in Patients with Inflammatory Bowel Disease in England: A Record Linkage Study (2016)
Journal Article

Background and Aims: Numerous studies have established that mortality risk in IBD patients is higher than the general population, but the causes of death have seldom been examined. We aimed to describe causes of death in IBD. Methods: A matched co... Read More about The Pattern of Underlying Cause of Death in Patients with Inflammatory Bowel Disease in England: A Record Linkage Study.

Ustekinumab: a novel therapeutic option in Crohn's disease (2016)
Journal Article

Tofacitinib in ulcerative colitis (2016)
Journal Article

Cytokines orchestrate immune and inflammatory responses involved in the pathogenesis of ulcerative colitis (UC). Protein kinases are essential for signal transduction in eukaryotic cells. Janus kinases (JAKs) are a family of protein tyrosine kinases... Read More about Tofacitinib in ulcerative colitis.

Ustekinumab for the treatment of Crohn's disease: can it find its niche? (2015)
Journal Article

Crohn’s disease is an immune-mediated disease that results in panenteric chronic inflammation in genetically predisposed individuals exposed to an appropriate environment. The past two decades have witnessed the emergence of an important class of dru... Read More about Ustekinumab for the treatment of Crohn's disease: can it find its niche?.

Magnetic resonance imaging biomarkers of gastrointestinal motor function and fluid distribution (2015)
Journal Article

Magnetic resonance imaging (MRI) is a well established technique that has revolutionized diagnostic radiology. Until recently, the impact that MRI has had in the assessment of gastrointestinal motor function and bowel fluid distribution in health and... Read More about Magnetic resonance imaging biomarkers of gastrointestinal motor function and fluid distribution.

Clinical predictors of thiopurine-related adverse events in Crohn's disease (2015)
Journal Article

Colectomy is a risk factor for venous thromboembolism in ulcerative colitis (2015)
Journal Article

AIM: To compare venous thromboembolism (VTE) in hospitalized ulcerative colitis (UC) patients who respond to medical management to patients requiring colectomy. METHODS: Population-based surveillance from 1997 to 2009 was used to identify all adults... Read More about Colectomy is a risk factor for venous thromboembolism in ulcerative colitis.

Phenotypic Features of Crohn's Disease Associated With Failure of Medical Treatment (2014)
Journal Article

Novel concepts in inflammatory bowel disease (2014)
Journal Article