The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways

Jerjees, Dena A.; Negm, Ola H.; Alabdullah, M. Layth; Mirza, Sameer; Alkaabi, Methaq; Hameed, Mohamed R.; Abduljabbar, Rezvan; Muftah, Abir; Nolan, Chris C.; Green, Andrew R.; Tighe, Patrick J.; Band, Vimla; Ellis, Ian O.; Rakha, Emad A.

doi:10.1007/s10549-015-3308-4

All Outputs (2)

Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer (2015)
Journal Article
Abduljabbar, R., Al-Kaabi, M. M., Negm, O. H., Jerjees, D., Muftah, A. A., Mukherjee, A., …Rakha, E. (2015). Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer. Breast Cancer Research and Treatment, 150(3), 511-522. https://doi.org/10.1007/s10549-015-3348-9

The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways (2015)
Journal Article
Jerjees, D. A., Negm, O. H., Alabdullah, M. L., Mirza, S., Alkaabi, M., Hameed, M. R., …Rakha, E. A. (2015). The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways. Breast Cancer Research and Treatment, 150(1), 91-103. https://doi.org/10.1007/s10549-015-3308-4

The mammalian target of rapamycin complex 1 (mTORC1) is a downstream of the PI3K/Akt pathway which affects cancer development. mTORC1 has many downstream signalling effectors that can enhance different cellular responses. This study aims to investiga... Read More about The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways.