Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis

Aldholmi, Mohammed; Ahmad, Rizwan; Carretero-Molina, Daniel; Pérez-Victoria, Ignacio; Martín, Jesús; Reyes, Fernando; Genilloud, Olga; Gourbeyre, Léa; Gefflaut, Thierry; Carlsson, Hanne; Maklakov, Alexei; Field, Robert A.; O'Neill, Ellis; Wilkinson, Barrie; O'Connell, Maria; Ganesan, A.

doi:10.1002/anie.202203175

All Outputs (3)

Glycosylated proteins in the protozoan alga Euglena gracilis: a proteomic approach (2022)
Journal Article

Protein glycosylation, and in particular N-linked glycans, is a hallmark of eukaryotic cells and has been well-studied in mammalian cells and parasites. However, little research has been conducted to investigate the conservation and variation of prot... Read More about Glycosylated proteins in the protozoan alga Euglena gracilis: a proteomic approach.

Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world (2022)
Journal Article

Euglenoids (Euglenida) are unicellular flagellates possessing exceptionally wide geographical and ecological distribution. Euglenoids combine a biotechnological potential with a unique position in the eukaryotic tree of life. In large part these micr... Read More about Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world.

Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis (2022)
Journal Article

By limiting the nitrogen source to glutamic acid, we isolated cyclic peptides from Euglena gracilis containing asparagine and non-proteinogenic amino acids. Structure elucidation was accomplished through spectroscopic methods, mass spectrometry and c... Read More about Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis.