Molecular Design of Squalene/Squalane Countertypes via the Controlled Oligomerization of Isoprene and Evaluation of Vaccine Adjuvant Applications
(2015)
Journal Article
Adlington, K., El harfi, J., Li, J., Carmichael, K., Guderian, J. A., Fox, C. B., & Irvine, D. (2015). Molecular Design of Squalene/Squalane Countertypes via the Controlled Oligomerization of Isoprene and Evaluation of Vaccine Adjuvant Applications. Biomacromolecules, 17(1), 165-172. doi:10.1021/acs.biomac.5b01285
The potential to replace shark-derived squalene in vaccine adjuvant applications with synthetic squalene/poly(isoprene) oligomers, synthesized by the controlled oligomerization of isoprene is demonstrated. Following on from our previous work regardin... Read More about Molecular Design of Squalene/Squalane Countertypes via the Controlled Oligomerization of Isoprene and Evaluation of Vaccine Adjuvant Applications.