Genetic variation in  HSD17B13  reduces the risk of developing cirrhosis and hepatocellular carcinoma in alcohol misusers

Stickel, Felix; Lutz, Philipp; Buch, Stephan; Nischalke, Hans Dieter; Silva, Ines; Rausch, Vanessa; Fischer, Janett; Weiss, Karl Heinz; Gotthardt, Daniel; Rosendahl, Jonas; Marot, Astrid; Elamly, Mona; Krawczyk, Marcin; Casper, Markus; Lammert, Frank; Buckley, Thomas WM; McQuillin, Andrew; Spengler, Ulrich; Eyer, Florian; Vogel, Arndt; Marhenke, Silke; Felden, Johann von; Wege, Henning; Sharma, Rohini; Atkinson, Stephen; Franke, Andre; Nehring, Sophie; Moser, Vincent; Schafmayer, Clemens; Spahr, Laurent; Lackner, Carolin; Stauber, Rudolf E.; Canbay, Ali; Link, Alexander; Valenti, Luca; Grove, Jane I.; Aithal, Guruprasad P.; Marquardt, Jens U.; Fateen, Waleed; Zopf, Steffen; Dufour, Jean-Francois; Trebicka, Jonel; Datz, Christian; Deltenre, Pierre; Mueller, Sebastian; Berg, Thomas; Hampe, Jochen; Morgan, Marsha Y

doi:10.1002/hep.30996

All Outputs (2)

Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study (2023)
Journal Article

Background: Liver cirrhosis is a major cause of death worldwide. Cirrhosis develops after a long asymptomatic period of fibrosis progression, with the diagnosis frequently occurring late, when major complications or cancer develop. Few reliable tools... Read More about Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study.

Genetic variation in HSD17B13 reduces the risk of developing cirrhosis and hepatocellular carcinoma in alcohol misusers (2020)
Journal Article

Background & Aims: Carriage of rs738409:G in patatin-like phospholipase domain-containing 3 (PNPLA3) is associated with an increased risk for developing alcohol-related cirrhosis and hepatocellular carcinoma (HCC). Recently, rs72613567:TA in hydrox... Read More about Genetic variation in HSD17B13 reduces the risk of developing cirrhosis and hepatocellular carcinoma in alcohol misusers.