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All Outputs (120)

Effect of oral prednisolone on symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection: a randomized clinical trial (2017)
Journal Article
Hay, A. D., Little, P., Harnden, A., Thompson, M., Wang, K., Kendrick, D., Orton, E., Brookes, S. T., Young, G. J., May, M., Hollinghurst, S., Carroll, F. E., Downing, H., Timmins, D., Lafond, N., El-Gohary, M., & Moore, M. (2017). Effect of oral prednisolone on symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection: a randomized clinical trial. Journal of the American Medical Association, 318(8), 721-730. https://doi.org/10.1001/jama.2017.10572

© 2017 American Medical Association. All rights reserved. IMPORTANCE: Acute lower respiratory tract infection is common and often treated inappropriately in primary care with antibiotics. Corticosteroids are increasingly used but without sufficient e... Read More about Effect of oral prednisolone on symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection: a randomized clinical trial.

Keeping children safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives (2017)
Journal Article
Kendrick, D., Ablewhite, J., Achana, F., Benford, P., Clacy, R., Coffey, F., Cooper, N., Coupland, C., Deave, T., Goodenough, T., Hawkins, A., Hayes, M., Hindmarch, P., Hubbard, S., Kay, B., Kumar, A., Majsak-Newman, G., McColl, E., McDaid, L., Miller, P., …Zou, K. (2017). Keeping children safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives. Programme Grants for Applied Research, 5(14), https://doi.org/10.3310/pgfar05140

Background: Unintentional injuries among 0- to 4-year-olds are a major public health problem incurring substantial NHS, individual and societal costs. However, evidence on the effectiveness and cost-effectiveness of preventative interventions is lack... Read More about Keeping children safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives.

Psychological morbidity and return to work after injury: multicentre cohort study (2017)
Journal Article
Kendrick, D., Dhiman, P., Kellezi, B., Coupland, C., Whitehead, J., Beckett, K., Christie, N., Sleney, J., Barnes, J., Joseph, S., & Morriss, R. (in press). Psychological morbidity and return to work after injury: multicentre cohort study. British Journal of General Practice, https://doi.org/10.3399/bjgp17X691673

Background: The benefits of work for physical, psychological and financial wellbeing are well documented. Return to work (RTW) after unintentional injury is often delayed, and psychological morbidity may contribute to this delay. The impact of psycho... Read More about Psychological morbidity and return to work after injury: multicentre cohort study.

Factors influencing the decision to attend screening for cancer in the UK: a meta-ethnography of qualitative research (2017)
Journal Article
Young, B., Bedford, L., Kendrick, D., Vedhara, K., Robertson, J., & das Nair, R. (in press). Factors influencing the decision to attend screening for cancer in the UK: a meta-ethnography of qualitative research. Journal of Public Health, https://doi.org/10.1093/pubmed/fdx026

Background: This review aimed to better understand experiences of being invited to cancer screening and associated decision-making.
Methods: Qualitative evidence explaining UK cancer screening attendance decisions was systematically identified. Data... Read More about Factors influencing the decision to attend screening for cancer in the UK: a meta-ethnography of qualitative research.

Child injury prevention: a survey of local authorities and health boards (2017)
Journal Article
Chisholm, A., Watson, M. C., Jones, S. J., & Kendrick, D. (in press). Child injury prevention: a survey of local authorities and health boards. International Journal of Health Promotion and Education, 55(4), https://doi.org/10.1080/14635240.2017.1312479

Aims: Unintentional home injuries are a significant global public health issue and are a major cause of mortality and morbidity. Within each country, injuries disproportionately affect children from low income families. Recent guidance issued in the... Read More about Child injury prevention: a survey of local authorities and health boards.

Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: cluster randomised controlled trial (2017)
Journal Article
Deave, T., Hawkins, A., Kumar, A., Hayes, M., Cooper, N., Watson, M., Ablewhite, J., Coupland, C., Sutton, A., Majsak-Newman, G., McDaid, L., Goodenough, T., Beckett, K., McColl, E., Reading, R., & Kendrick, D. (2017). Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: cluster randomised controlled trial. PLoS ONE, 12(3), Article e0172584. https://doi.org/10.1371/journal.pone.0172584

Background: Many developed countries have high mortality rates for fire-related deaths in children aged 0–14 years with steep social gradients. Evidence-based interventions to promote fire safety practices exist, but the impact of implementing a rang... Read More about Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: cluster randomised controlled trial.

Use of conspicuity aids by cyclists and risk of crashes involving other road users: population based case-control study (2017)
Journal Article
Miller, P., Kendrick, D., Coupland, C., & Coffey, F. (in press). Use of conspicuity aids by cyclists and risk of crashes involving other road users: population based case-control study. Journal of Transport and Health, 7(A), https://doi.org/10.1016/j.jth.2017.03.008

Background: Cycling can improve health and well-being by reducing inactivity. Concern about collision crashes may be a barrier to participation since collision crashes can lead to significant mortality and morbidity. The conspicuity of cyclists may b... Read More about Use of conspicuity aids by cyclists and risk of crashes involving other road users: population based case-control study.

Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial (2017)
Journal Article
Sullivan, F., Farmer, E., Mair, F. S., Treweek, S., Kendrick, D., Jackson, C., Robertson, C., Briggs, A., McCowan, C., Bedford, L., Young, B., Vedhara, K., Gallant, S., Littleford, R., Robertson, J., Sewell, H., Dorward, A., Sarvesvaran, J., & Schembri, S. (2017). Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial. BMC Cancer, 17(1), https://doi.org/10.1186/s12885-017-3175-y

Background: Lung cancer is the most common cause of cancer related death worldwide. The majority of cases are detected at a late stage when prognosis is poor. The EarlyCDT®-Lung Test detects autoantibodies to abnormal cell surface proteins in the ear... Read More about Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial.

Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England (2017)
Journal Article
Baker, R., Kendrick, D., Tata, L. J., & Orton, E. (2017). Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England. Injury Prevention, 23(6), 396-402. https://doi.org/10.1136/injuryprev-2016-042294

Background: Maternal depression is common and associated with several child health outcomes. The impact on childhood injuries is underexplored, with existing studies relying on maternal reporting of injury occurrences. Using population healthcare dat... Read More about Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England.

Poison prevention practices and medically attended poisoning in young children: multicentre case-control study (2016)
Journal Article
Kendrick, D., Majsak-Newman, G., Benford, P., Coupland, C., Timblin, C., Hayes, M., Goodenough, T., Hawkins, A., & Reading, R. (2017). Poison prevention practices and medically attended poisoning in young children: multicentre case-control study. Injury Prevention, 23(2), 93-101. https://doi.org/10.1136/injuryprev-2015-041828

Introduction

Childhood poisonings are common, placing a substantial burden on health services. Case-control studies have found inconsistent evidence about modifiable risk factors for poisonings amongst 0-4 year olds. This study quantifies associat... Read More about Poison prevention practices and medically attended poisoning in young children: multicentre case-control study.

The impact of psychological factors on recovery from injury: a multicentre cohort study (2016)
Journal Article
Kellezi, B., Coupland, C., Morriss, R., Beckett, K., Joseph, S., Barnes, J., Christie, N., Sleney, J., & Kendrick, D. (2016). The impact of psychological factors on recovery from injury: a multicentre cohort study. Social Psychiatry and Psychiatric Epidemiology, 52(7), https://doi.org/10.1007/s00127-016-1299-z

Purpose
Unintentional injuries have a significant long-term health impact in working age adults. Depression, anxiety and post-traumatic stress disorder are common post-injury, but their impact on self-reported recovery has not been investigated in g... Read More about The impact of psychological factors on recovery from injury: a multicentre cohort study.

Psychological morbidity and health related quality of life after injury: multicentre cohort study (2016)
Journal Article
Kendrick, D., Kellezi, B., Coupland, C., Maula, A., Beckett, K., Morriss, R. K., Joseph, S., Barnes, J., Sleney, J., & Christie, N. (2017). Psychological morbidity and health related quality of life after injury: multicentre cohort study. Quality of Life Research, 26(5), 1233-1250. https://doi.org/10.1007/s11136-016-1439-7

Purpose: To demonstrate the impact of psychological morbidity one month post-injury on subsequent post-injury quality of life (HRQoL) in a general injury population in the UK to inform development of trauma care and rehabilitation services.

Method... Read More about Psychological morbidity and health related quality of life after injury: multicentre cohort study.

The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency (2016)
Journal Article
Sahota, O., Pulikottil-Jacob, R., Marshall, F., Montgomery, A., Tan, W., Sach, T., Logan, P., Kendrick, D., Watson, A., Walker, M., & Waring, J. (in press). The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency. Age and Ageing, 46(1), https://doi.org/10.1093/ageing/afw149

Objective: To compare the clinical and cost-effectiveness of a Community In-reach Rehabilitation and Care Transition (CIRACT) service with the traditional hospital-based rehabilitation (THB-Rehab) service.

Design: Pragmatic randomised controlled... Read More about The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency.

Modifiable risk factors for scald injury in children under 5 years of age: a multi-centre case–control study (2016)
Journal Article
Stewart, J., Benford, P., Wynn, P., Watson, M. C., Coupland, C., Deave, T., Hindmarch, P., Majsak-Newman, G., & Kendrick, D. (2016). Modifiable risk factors for scald injury in children under 5 years of age: a multi-centre case–control study. Burns, 42(8), 1831-1843. https://doi.org/10.1016/j.burns.2016.06.027

Objective: To determine the relationship between a range of modifiable risk factors and medically attended scalds in children under the age of 5 years.
Methods: Multicentre matched case-control study in acute hospitals, minor injury units and GP pr... Read More about Modifiable risk factors for scald injury in children under 5 years of age: a multi-centre case–control study.

Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study (2016)
Journal Article
Tyrrell, E. G., Orton, E., Sayal, K., Baker, R., & Kendrick, D. (2017). Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study. Journal of Public Health, 39(2), Article e1-e9. https://doi.org/10.1093/pubmed/fdw075

Background Accurate and up to date data on changes in poisoning incidence among young people are lacking. Recent linkage of UK primary care, hospital and mortality data allows these to be quantified to inform service delivery.

Methods An open coh... Read More about Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study.

A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children (2016)
Journal Article
Achana, F., Sutton, A. J., Kendrick, D., Hayes, M., Jones, D. R., Hubbard, S. J., & Cooper, N. J. (2016). A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children. BMC Public Health, 16, Article 705. https://doi.org/10.1186/s12889-016-3334-0

Background: Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-e... Read More about A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children.

Reducing falls among older people in general practice: the ProAct65+ exercise intervention trial (2016)
Journal Article
Gawler, S., Skelton, D. A., Dinan-Young, S., Masud, T., Morris, R. W., Griffin, M., Kendrick, D., & Iliffe, S. (2016). Reducing falls among older people in general practice: the ProAct65+ exercise intervention trial. Archives of Gerontology and Geriatrics, 67, https://doi.org/10.1016/j.archger.2016.06.019

Background: Falls are common in the older UK population and associated costs to the NHS are high. Systematic reviews suggest that home exercise and group-based exercise interventions, which focus on progressively challenging balance and increasing st... Read More about Reducing falls among older people in general practice: the ProAct65+ exercise intervention trial.

Differing patterns in thermal injury incidence and hospitalisations among 0–4 year old children from England (2016)
Journal Article
Baker, R., Tata, L. J., Kendrick, D., Burch, T., Kennedy, M., & Orton, E. (2016). Differing patterns in thermal injury incidence and hospitalisations among 0–4 year old children from England. Burns, 42(7), 1609-1616. https://doi.org/10.1016/j.burns.2016.05.007

Objective: To describe patterns in thermal injury incidence and hospitalisations by age, sex, calendar year and socioeconomic status among 0-4 year olds in England for the period 1998-2013.

Participants: 708,050 children with linked primary care a... Read More about Differing patterns in thermal injury incidence and hospitalisations among 0–4 year old children from England.

Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data (2016)
Journal Article
Baker, R., Orton, E., Tata, L. J., & Kendrick, D. (2016). Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data. European Journal of Public Health, 26(6), 940-946. https://doi.org/10.1093/eurpub/ckw064

Background:
Understanding patterns of injury in England is challenging due to a lack of national injury surveillance data. Through recent linkage of a large primary care research database to hospitalization and mortality data, we describe the epide... Read More about Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data.