Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study

Tyrrell, Edward G.; Orton, Elizabeth; Sayal, Kapil; Baker, Ruth; Kendrick, Denise

Abstract

Background Accurate and up to date data on changes in poisoning incidence among young people are lacking. Recent linkage of UK primary care, hospital and mortality data allows these to be quantified to inform service delivery.

Methods An open cohort study of 1 736 527 young people aged 10–24 between 1998 and 2014 was conducted using linked data from the Clinical Practice Research Datalink, Hospital Episode Statistics and Office for National Statistics deaths. Incidence rates (IRs) by poisoning intent were calculated by age, sex, deprivation and year.


Results Total poisoning IRs increased by 25% from 1998/99 to 2013/14 [adjusted incidence rate ratio (aIRR) 1.25, 95% CI: 1.20–1.30]. Patterns differed markedly by intent. Intentional poisoning rates increased by 52% while unintentional rates remained unchanged. Intentional rates increased almost exclusively among females, gradually between 1998/99 and 2013/14 among 16–18 (88% increase) and 19–24 (36% increase) year olds but only increased among 10–15 year olds in the last 2 years (79% increase). A 2-fold increased risk of poisoning for the most compared to least deprived quintile existed (aIRR 2.21, 95% CI: 2.02–2.23) and remained over time.

Conclusions Commissioning of primary and secondary prevention services needs to address the growing problem of intentional poisonings among young people.

Citation

Tyrrell, E. G., Orton, E., Sayal, K., Baker, R., & Kendrick, D. (2017). Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study. Journal of Public Health, 39(2), Article e1-e9. https://doi.org/10.1093/pubmed/fdw075

• Journal Article Type: Article
• Acceptance Date: Jul 7, 2016
• Online Publication Date: Aug 13, 2016
• Publication Date: Jun 1, 2017
• Deposit Date: Aug 23, 2016
• Publicly Available Date: Aug 23, 2016
• Journal: Journal of Public Health
• Print ISSN: 1741-3842
• Electronic ISSN: 1741-3850
• Publisher: Oxford University Press
• Peer Reviewed: Peer Reviewed
• Volume: 39
• Issue: 2
• Article Number: e1-e9
• DOI: https://doi.org/10.1093/pubmed/fdw075
• Keywords: epidemiology; mental health; young people
• Public URL: https://nottingham-repository.worktribe.com/output/863475
• Publisher URL: https://academic.oup.com/jpubhealth/article/39/2/e1/3002999/Differing-patterns-in-intentional-and?guestAccessKey=03061404-d2d0-47b4-a468-da764712c0fc
• Additional Information: This is a pre-copyedited, author-produced PDF of an article accepted for publication in the Journal of Public Health following peer review. The version of record for Tyrrell E.G., Orton E., Sayal K., Baker R., Kendrick, D. Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study. Journal of Public Health 2016; First published online: 13 August 2016:doi:10.1093/pubmed/fdw075 is available online at: https://academic.oup.com/jpubhealth/article/39/2/e1/3002999/Differing-patterns-in-intentional-and?guestAccessKey=03061404-d2d0-47b4-a468-da764712c0fc
• Contract Date: Aug 23, 2016