All Outputs (120)

Five year mortality in an RCT of a lung cancer biomarker to select people for low dose CT screening (2025)
Journal Article
Sullivan, F. M., Mair, F. S., Anderson, W., Chew, C., Dorward, A., Haughney, J., Hogarth, F., Kendrick, D., Littleford, R., McConnachie, A., McCowan, C., McMeekin, N., Patel, M., Rauchhaus, P., Daly, F., Ritchie, L., Robertson, J., Sarvesvaran, J., Sewell, H., Taylor, T., …Schembri, S. (2025). Five year mortality in an RCT of a lung cancer biomarker to select people for low dose CT screening. PLoS ONE, 20(1), Article e0306163. https://doi.org/10.1371/journal.pone.0306163

The role of biomarkers in risk-based early detection of lung cancer may enable screening to become cost effective and widely accessible. EarlyCDT-Lung is an example of such a blood-based autoantibody biomarker which may improve accessibility to Low d... Read More about Five year mortality in an RCT of a lung cancer biomarker to select people for low dose CT screening.

Communities of Practice (CoP) - a public health tool for facilitating implementation of research into practice for a falls prevention exercise intervention; an ethnographic study (2024)
Preprint / Working Paper
Orton, E., Alderman, V., Carpenter, H., Coupland, C., Gladman, J., Iliffe, S., Kendrick, D., Lafond, N., Logan, P., Okereke, U., Skelton, D., Masud, T., & Timmons, S. (2024). Communities of Practice (CoP) - a public health tool for facilitating implementation of research into practice for a falls prevention exercise intervention; an ethnographic study

Introduction
In public health there is often a disconnect in translating research into practice.
The Falls Management Exercise (FaME) programme is an evidence-based exercise programme aimed at reducing falls in older adults. Whilst recommended as... Read More about Communities of Practice (CoP) - a public health tool for facilitating implementation of research into practice for a falls prevention exercise intervention; an ethnographic study.

Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach (2024)
Journal Article
Radford, K., Kettlewell, J., das Nair, R., Morriss, R., Holmes, J., Kellezi, B., Timmons, S., Jones, T., Tressider, H., Andrews, I., Bridger, K., Patel, P., Lindley, R., De Dios Perez, B., Statham, A., Jones, T., Hoffman, K., James, M., Kendrick, D., & ROWTATE study team. (2024). Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach. BMJ Open, 14(10), Article e085724. https://doi.org/10.1136/bmjopen-2024-085724

Objectives: Major trauma centres save lives but rehabilitation to support return-to-work (RTW) is lacking. This paper describes development of a vocational rehabilitation intervention (the ROWTATE intervention) to support RTW following traumatic inju... Read More about Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach.

Mixed-methods evaluation of the Falls Management Exercise (FaME) Programme Implementation Toolkit (2024)
Preprint / Working Paper
Singh, S., Kendrick, D., Vickers, R., & Orton, E. (2024). Mixed-methods evaluation of the Falls Management Exercise (FaME) Programme Implementation Toolkit

Background
The Falls Management Exercise (FaME) programme has been shown to be effective in reducing falls in older adults. This study explores how a falls prevention toolkit (FaME toolkit) can be improved to increase adoption and fidelity of FaME.... Read More about Mixed-methods evaluation of the Falls Management Exercise (FaME) Programme Implementation Toolkit.

Cost-effectiveness of the ‘Stay One Step Ahead’ Home Safety programme for the prevention of injuries among children under 5 years (2024)
Journal Article
Jones, M., Orton, E., Taylor, M. J., Timblin, C., Clarke, R., Watson, M. C., Hayes, M., Patel, T., Coupland, C., & Kendrick, D. (2024). Cost-effectiveness of the ‘Stay One Step Ahead’ Home Safety programme for the prevention of injuries among children under 5 years. Injury Prevention, https://doi.org/10.1136/ip-2024-045236

Background Unintentional injuries are a common cause of morbidity and mortality in the under-5s, but undertaking home safety practices can reduce injury risk. Stay One Step Ahead (SOSA) is an evidence-based standardised home safety programme. This st... Read More about Cost-effectiveness of the ‘Stay One Step Ahead’ Home Safety programme for the prevention of injuries among children under 5 years.

What affects implementation of the UK major trauma rehabilitation prescription? A survey informed by the behaviour change wheel (2024)
Journal Article
Kettlewell, J., Radford, K., Timmons, S., Jones, T., Fallon, S., Westley, R., White, S., & Kendrick, D. (2024). What affects implementation of the UK major trauma rehabilitation prescription? A survey informed by the behaviour change wheel. Injury, Article 111722. https://doi.org/10.1016/j.injury.2024.111722

Objective: Major trauma 'Rehabilitation Prescriptions' aim to facilitate continuity of care and describe patient needs following discharge from UK Major Trauma Centre (MTCs), however research suggests rehabilitation prescriptions are not being implem... Read More about What affects implementation of the UK major trauma rehabilitation prescription? A survey informed by the behaviour change wheel.

Early vocational rehabilitation and psychological support for trauma patients to improve return to work (the ROWTATE trial): study protocol for an individually randomised controlled multicentre pragmatic trial (2024)
Journal Article
Kendrick, D., Lindley, R., Blackburn, L., Roadevin, C., Thompson, E., Andrews, I., Anwar, F., Brooks, A., Carlton, E., Crouch, R., Day, F., Fallon, S., Farrin, A., Graham, L., Hoffman, K., Howell, R., Holmes, J., James, M., Jones, T., Kellezi, B., …Radford, K. (2024). Early vocational rehabilitation and psychological support for trauma patients to improve return to work (the ROWTATE trial): study protocol for an individually randomised controlled multicentre pragmatic trial. Trials, 25(1), Article 439. https://doi.org/10.1186/s13063-024-08183-w

Background
Moderately severe or major trauma (injury severity score (ISS) > 8) is common, often resulting in physical and psychological problems and leading to difficulties in returning to work. Vocational rehabilitation (VR) can improve return to w... Read More about Early vocational rehabilitation and psychological support for trauma patients to improve return to work (the ROWTATE trial): study protocol for an individually randomised controlled multicentre pragmatic trial.

Patterns and trends of medicinal poisoning substances: a population-based cohort study of injuries in 0-11 year old children from 1998-2018 (2024)
Journal Article
Tyrrell, E. G., Orton, E., Tata, L. J., & Kendrick, D. (2024). Patterns and trends of medicinal poisoning substances: a population-based cohort study of injuries in 0-11 year old children from 1998-2018. Archives of Public Health, 82(1), Article 50. https://doi.org/10.1186/s13690-024-01268-7

Background
There have been sharp increases in antidepressant and opioid prescriptions over the last 10 years, as well as increased over-the-counter medicine availability. However, the impact on childhood medicinal poisonings rates, particularly by s... Read More about Patterns and trends of medicinal poisoning substances: a population-based cohort study of injuries in 0-11 year old children from 1998-2018.

Evaluating the effect of child home safety training upon three family support practitioner groups: a mixed-methods study (2023)
Journal Article
Taylor, M. J., Patel, T., Orton, E., Watson, M. C., Hayes, M., Stewart, S., Clarke, R., Timblin, C., & Kendrick, D. (2023). Evaluating the effect of child home safety training upon three family support practitioner groups: a mixed-methods study. Perspectives in Public Health, https://doi.org/10.1177/17579139231185999

Aims:
Unintentional injuries in the home contribute substantially to preschool child morbidity and mortality. Practitioners such as health visitors, family mentors and children’s centre staff are well-positioned to facilitate child injury prevention... Read More about Evaluating the effect of child home safety training upon three family support practitioner groups: a mixed-methods study.

Implementation fidelity of the ‘Stay One Step Ahead’ home safety intervention: a mixed-methods analysis (2023)
Journal Article
Stewart, S., Kendrick, D., Watson, M. C., Hayes, M., & Orton, E. (2023). Implementation fidelity of the ‘Stay One Step Ahead’ home safety intervention: a mixed-methods analysis. Injury Prevention, 29(4), 340-346. https://doi.org/10.1136/ip-2023-044855

Objective: To assess implementation fidelity of the Stay One Step Ahead (SOSA), a complex intervention which was delivered by health visiting teams, children's centres, and family mentors and was aimed at preventing unintentional home injuries in chi... Read More about Implementation fidelity of the ‘Stay One Step Ahead’ home safety intervention: a mixed-methods analysis.

Effectiveness of systematically delivered evidence-based home safety promotion to improve child home safety practices: a controlled before-and-after study (2023)
Journal Article
Taylor, M. J., Orton, E., Patel, T., Timblin, C., Clarke, R., Watson, M. C., Hayes, M., Jones, M., Coupland, C., & Kendrick, D. (2023). Effectiveness of systematically delivered evidence-based home safety promotion to improve child home safety practices: a controlled before-and-after study. Injury Prevention, 29(3), 227-233. https://doi.org/10.1136/ip-2022-044745

Objective: Evaluate the effectiveness of systematically delivered evidence-based home safety promotion for improving child home safety practices. Design: Controlled before-and-after study. Setting: Nine electoral wards in Nottingham, UK. Participants... Read More about Effectiveness of systematically delivered evidence-based home safety promotion to improve child home safety practices: a controlled before-and-after study.

Cost-effectiveness of England's national 'Safe At Home' scheme for reducing hospital admissions for unintentional injury in children aged under 5 (2022)
Journal Article
Jones, M., Hill, T., Coupland, C., Kendrick, D., Akbari, A., Rodgers, S., Watson, M. C., Tyrrell, E., Merrill, S., Martin, A., & Orton, E. (2022). Cost-effectiveness of England's national 'Safe At Home' scheme for reducing hospital admissions for unintentional injury in children aged under 5. Injury Prevention, https://doi.org/10.1136/ip-2022-044698

Background: Injuries in children aged under 5 years most commonly occur in the home and disproportionately affect those living in the most disadvantaged communities. The 'Safe at Home' (SAH) national home safety equipment scheme, which ran in England... Read More about Cost-effectiveness of England's national 'Safe At Home' scheme for reducing hospital admissions for unintentional injury in children aged under 5.

Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial (2022)
Journal Article
Hawkey, C., Avery, A., Coupland, C. A., Crooks, C., Dumbleton, J., Hobbs, F. D. R., Kendrick, D., Moore, M., Morris, C., Rubin, G., Smith, M., Stevenson, D., Mant, D., Ford, A., Macdonald, T., Bradburn, M., Ward, C., Shone, A., Logan, R., McColl, K., …Hodgson, S. (2022). Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial. Lancet, 400(10363), 1597-1606. https://doi.org/10.1016/S0140-6736%2822%2901843-8

Background: Peptic ulcers in patients receiving aspirin are associated with Helicobacter pylori infection. We aimed to investigate whether H pylori eradication would protect against aspirin-associated ulcer bleeding. Methods: We conducted a randomise... Read More about Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial.

P04-07 Factors associated with maintenance of physical activity in older adults undertaking a strength and balance programme for falls prevention (2022)
Journal Article
Blackmore, C., Kendrick, D., & Orton, E. (2022). P04-07 Factors associated with maintenance of physical activity in older adults undertaking a strength and balance programme for falls prevention. European Journal of Public Health, 32(Supplement_2), Article ckac095.061. https://doi.org/10.1093/eurpub/ckac095.061

Abstract Background Falls are a major cause of mortality and morbidity in older adults worldwide, yet those who are more physically active have a lower risk of falling. There is little information on which participants are most likely to complete fal... Read More about P04-07 Factors associated with maintenance of physical activity in older adults undertaking a strength and balance programme for falls prevention.

Qualitative study exploring factors affecting the implementation of a vocational rehabilitation intervention in the UK major trauma pathway (2022)
Journal Article
Kettlewell, J., Radford, K., Kendrick, D., Patel, P., Bridger, K., Kellezi, B., Das Nair, R., Jones, T., & Timmons, S. (2022). Qualitative study exploring factors affecting the implementation of a vocational rehabilitation intervention in the UK major trauma pathway. BMJ Open, 12(3), Article e060294. https://doi.org/10.1136/bmjopen-2021-060294

Objectives This study aimed to: (1) understand the context for delivering a trauma vocational rehabilitation (VR) intervention; (2) identify potential barriers and enablers to the implementation of a VR intervention post-trauma. Design Qualitative st... Read More about Qualitative study exploring factors affecting the implementation of a vocational rehabilitation intervention in the UK major trauma pathway.

Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial (2022)
Journal Article
Hancox, J., Ayling, K., Bedford, L., Vedhara, K., Robertson, J. F. R., Young, B., das Nair, R., Sullivan, F. M., Schembri, S., Mair, F. S., Littleford, R., & Kendrick., D. (2023). Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial. Journal of Public Health, 45(2), e275–e284. https://doi.org/10.1093/pubmed/fdac032

Background: The Early CDT®-Lung antibody blood test plus serial CT-scans for test-positives reduces late-stage lung cancer presentation. This study assessed psychological outcomes of this approach.

Methods: Randomised controlled trial (n=12,208) c... Read More about Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial.

Patients views on which return-to-work outcomes should be prioritised: A nominal group technique focus group (2022)
Journal Article
Bridger, K., Kellezi, B., Kendrick, D., Kettlewell, J., Holmes, J., Timmons, S., Andrews, I., Fallon, S., & Radford, K. (2022). Patients views on which return-to-work outcomes should be prioritised: A nominal group technique focus group. British Journal of Occupational Therapy, 85(9), 704-711. https://doi.org/10.1177/03080226211072766

Objective: Injuries can have a long-lasting effect on ability to return to work, but there is little research on which outcomes are most important to patients. This study aims to identify and prioritise return-to-work outcomes important to patients f... Read More about Patients views on which return-to-work outcomes should be prioritised: A nominal group technique focus group.

Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT) (2022)
Journal Article
Stevenson, D. J., Avery, A. J., Coupland, C., Hobbs, F. D. R., Kendrick, D., Moore, M. V., Morris, C., Rubin, G. P., Smith, M. D., Hawkey, C. J., & Dumbleton, J. S. (2022). Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT). Trials, 23(1), Article 140. https://doi.org/10.1186/s13063-022-06054-w

Background: The Helicobacter Eradication Aspirin Trial (HEAT) is a multicentre, double blind, randomised controlled trial investigating whether Helicobacter (H.) pylori eradication reduces hospitalisation for peptic ulcer bleeding. Recruited particip... Read More about Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT).

‘It is designed for everybody to find their own level and to improve themselves’; views of older people and instructors of the Falls Management Exercise (FaME) programme (2022)
Journal Article
Gumber, L., Timmons, S., Coupland, C., Gladman, J., Lliffe, S., Kendrick, D., Lafond, N., Logan, P., Masud, T., Skelton, D., Timblin, C., & Orton, E. (2022). ‘It is designed for everybody to find their own level and to improve themselves’; views of older people and instructors of the Falls Management Exercise (FaME) programme. Age and Ageing, 51(2), Article afac023. https://doi.org/10.1093/ageing/afac023

Background: Older adults are at increased risk of falls due to ageing, decreased muscle strength and impaired balance. Clinical trials have demonstrated the efficacy and effectiveness of the Falls Management Exercise (FaME) programme in improving fun... Read More about ‘It is designed for everybody to find their own level and to improve themselves’; views of older people and instructors of the Falls Management Exercise (FaME) programme.

Using Forum Theatre to mobilise knowledge and improve NHS care: the Enhancing Post-injury Psychological Intervention and Care (EPPIC) study (2022)
Journal Article
Beckett, K., Deave, T., McBride, T., May, A. L., Gabbay, J., Kapoulas, U., Long, A., Warburton, G., Wogan, C., Cox, L., Thompson, J., Spencer, F., & Kendrick, D. (2022). Using Forum Theatre to mobilise knowledge and improve NHS care: the Enhancing Post-injury Psychological Intervention and Care (EPPIC) study. Evidence and Policy, 18(2), 236-264. https://doi.org/10.1332/174426421X16420902769508

Background: Evidence regarding the impact of psychological problems on recovery from injury has limited influence on practice. Mindlines show effective practice requires diverse knowledge which is generally socially transmitted. Aims and objectives:... Read More about Using Forum Theatre to mobilise knowledge and improve NHS care: the Enhancing Post-injury Psychological Intervention and Care (EPPIC) study.