Isoaspartate, Carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury

Carter, Wayne; Vigneswara, Vasanthy; Newlaczyl, Anna; Wayne, Declan; Ahmed, Bilal; Saddington, Stephen; Brewer, Charlotte; raut, Nikhilesh; Gerdes, Henry; Erdozain, Amaia; Tooth, David; Bolt, Edward; Osna, Natalie; Tuma, Dean; Kharbanda, Kusum

doi:10.1016/j.bbrc.2015.01.158

All Outputs (2)

Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin (2016)
Journal Article

Unanchored polyubiquitin chains are emerging as importanregulators of cellular physiology with diverse roles paralleling those of substrate-conjugated polyubiquitin. However tools able to discriminate unanchored polyubiquitin chains of different isop... Read More about Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin.

Isoaspartate, Carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury (2016)
Journal Article

We had previously shown that alcohol consumption can induce cellular isoaspartate protein damage via an impairment of the activity of protein isoaspartyl methyltransferase (PIMT), an enzyme that triggers repair of isoaspartate protein damage. To furt... Read More about Isoaspartate, Carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury.