All Outputs (5)

Taking a broader view of things: towards a transdisciplinary approach to cancer (2017)
Journal Article

Cancer is widely considered an abnormality that emerges from within the body and which must be destroyed and defeated. But we still do not know precisely how and why cancer starts, and while a ‘magic bullet’ cure has failed to materialise, those adop... Read More about Taking a broader view of things: towards a transdisciplinary approach to cancer.

A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions (2017)
Journal Article

All pharmaceutical companies are required to assess pharmacokinetic drug-drug interactions (DDIs) of new chemical entities (NCEs) and mathematical prediction helps to select the best NCE candidate with regard to adverse effects resulting from a DDI b... Read More about A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions.

Computed tomography in veterinary medicine: currently published and tomorrow’s vision (2017)
Book Chapter

The utilisation of Computed Tomography (CT) in veterinary practice has been increasing rapidly in line with reduced cost, improved availability and the increase in expertise and technology. This review briefly examines the recent technological advanc... Read More about Computed tomography in veterinary medicine: currently published and tomorrow’s vision.

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases (2017)
Journal Article

During the last few years, the understanding of the dysregulated hydrogen ion dynamics and reversed proton gradient of cancer cells has resulted in a new and integral pH-centric paradigm in oncology, a translational model embracing from cancer etiopa... Read More about Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases.

Physical and biological characteristics of multi drug resistance (MDR): an integral approach considering pH and drug resistance in cancer (2017)
Journal Article

The role of the Warburg effect in cancer remains to be elucidated with a resurgence in research efforts over the past decade. Why a cancer cell would prefer to use energy inefficient glycolysis, leading to an alteration of pH both inside and outside... Read More about Physical and biological characteristics of multi drug resistance (MDR): an integral approach considering pH and drug resistance in cancer.