Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold

Pitrolino, Katherine A.; Felfel, Reda M.; Pellizzeri, Laura Macri; McLaren, Jane; Popov, Alexander A.; Sottile, Virginie; Scotchford, Colin A.; Scammell, Brigitte E.; Roberts, George A.F.; Grant, David M.

doi:10.1016/j.carbpol.2022.119126

All Outputs (2)

Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation (2022)
Journal Article

Phosphate-based glasses (PBGs) are promising materials for bone repair and regeneration as they can be formulated to be compositionally similar to the inorganic components of bone. Alterations to the PBG formulation can be used to tailor their degrad... Read More about Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation.

Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold (2022)
Journal Article

An innovative approach was developed to engineer a multi-layered chitosan scaffold for osteochondral defect repair. A combination of freeze drying and porogen-leaching out methods produced a porous, bioresorbable scaffold with a distinct gradient of... Read More about Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold.