All Outputs (2)

ENTH and ANTH domain proteins participate in AP2-independent clathrin-mediated endocytosis (2015)
Journal Article
Manna, P. T., Gadelha, C., Puttick, A. E., & Field, M. C. (2015). ENTH and ANTH domain proteins participate in AP2-independent clathrin-mediated endocytosis. Journal of Cell Science, 128(11), https://doi.org/10.1242/jcs.167726

Clathrin-mediated endocytosis (CME) is a major route of entry into eukaryotic cells. A core of evolutionarily ancient genes encodes many components of this system but much of our mechanistic understanding of CME is derived from a phylogenetically nar... Read More about ENTH and ANTH domain proteins participate in AP2-independent clathrin-mediated endocytosis.

Architecture of a host–parasite interface: complex targeting mechanisms revealed through proteomics (2015)
Journal Article
Gadelha, C., Zhang, W., Chamberlain, J. W., Chait, B. T., Wickstead, B., & Field, M. C. (2015). Architecture of a host–parasite interface: complex targeting mechanisms revealed through proteomics. Molecular and Cellular Proteomics, 14(7), https://doi.org/10.1074/mcp.M114.047647

Surface membrane organization and composition is key to cellular function, and membrane proteins serve many essential roles in endocytosis, secretion, and cell recognition. The surface of parasitic organisms, however, is a double-edged sword; this is... Read More about Architecture of a host–parasite interface: complex targeting mechanisms revealed through proteomics.