Transcriptomic links to muscle mass loss and declines in cumulative muscle protein synthesis during short-term disuse in healthy younger humans

Willis, Craig R.G.; Gallagher, Iain J.; Wilkinson, Daniel J.; Brook, Matthew S.; Bass, Joseph J.; Phillips, Bethan E.; Smith, Kenneth; Etheridge, Timothy; Stokes, Tanner; McGlory, Chris; Gorissen, Stefan H.M.; Szewczyk, Nathaniel J.; Phillips, Stuart M.; Atherton, Philip J.

doi:10.1096/fj.202100276RR

All Outputs (1)

Transcriptomic links to muscle mass loss and declines in cumulative muscle protein synthesis during short-term disuse in healthy younger humans (2021)
Journal Article
Willis, C. R., Gallagher, I. J., Wilkinson, D. J., Brook, M. S., Bass, J. J., Phillips, B. E., …Atherton, P. J. (2021). Transcriptomic links to muscle mass loss and declines in cumulative muscle protein synthesis during short-term disuse in healthy younger humans. FASEB Journal, 35(9), Article e21830. https://doi.org/10.1096/fj.202100276RR

Muscle disuse leads to a rapid decline in muscle mass, with reduced muscle protein synthesis (MPS) considered the primary physiological mechanism. Here, we employed a systems biology approach to uncover molecular networks and key molecular candidates... Read More about Transcriptomic links to muscle mass loss and declines in cumulative muscle protein synthesis during short-term disuse in healthy younger humans.