All Outputs (7)

Optogenetic control of Drosophila neurons: a laboratory practical for undergraduates and outreach (2024)
Journal Article
Renault, A. D. (2024). Optogenetic control of Drosophila neurons: a laboratory practical for undergraduates and outreach. Journal of Microbiology and Biology Education, 25(3), Article e00086-24. https://doi.org/10.1128/jmbe.00086-24

Teaching aspects of neuroscience to large undergraduate classes can be difficult in terms of the cost of equipment involved such as microscopes and electrophysiology equipment, the time taken to master techniques such as dissection or intracellular r... Read More about Optogenetic control of Drosophila neurons: a laboratory practical for undergraduates and outreach.

The Lipid Phosphate Phosphatase Wunen Promotes Eggshell Formation and Is Essential for Fertility in Drosophila (2023)
Journal Article
Mukherjee, A., Schuppe, M., & Renault, A. D. (2023). The Lipid Phosphate Phosphatase Wunen Promotes Eggshell Formation and Is Essential for Fertility in Drosophila. Biology, 12(7), Article 1003. https://doi.org/10.3390/biology12071003

The eggshell that surrounds insect eggs acts as a barrier, protecting against biotic factors and desiccation. The eggshell is a multi-layered structure which is synthesised by the somatic follicle cells that surround the developing oocyte. Although t... Read More about The Lipid Phosphate Phosphatase Wunen Promotes Eggshell Formation and Is Essential for Fertility in Drosophila.

Hmgcr promotes a long-range signal to attract Drosophila germ cells independently of Hedgehog (2019)
Journal Article
Kenwrick, K., Mukherjee, A., & Renault, A. D. (2019). Hmgcr promotes a long-range signal to attract Drosophila germ cells independently of Hedgehog. Journal of Cell Science, 132(23), 1-14. https://doi.org/10.1242/jcs.232637

During development many cell types migrate along stereotyped routes determined through deployment of cell surface or secreted guidance molecules. Whilst we know the identity of many of these molecules, the distances over which they natively operate c... Read More about Hmgcr promotes a long-range signal to attract Drosophila germ cells independently of Hedgehog.

Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure (2014)
Journal Article
Haack, T., Schneider, M., Schwendele, B., & Renault, A. D. (2014). Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure. Developmental Biology, 396(2), https://doi.org/10.1016/j.ydbio.2014.08.033

The Drosophila heart is a linear organ formed by the movement of bilaterally specified progenitor cells to the midline and adherence of contralateral heart cells. This movement occurs through the attachment of heart cells to the overlying ectoderm wh... Read More about Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure.

Transcriptional regulation of Drosophila gonad formation (2014)
Journal Article
Tripathy, R., Kunwar, P. S., Sano, H., & Renault, A. D. (2014). Transcriptional regulation of Drosophila gonad formation. Developmental Biology, 392(2), https://doi.org/10.1016/j.ydbio.2014.05.026

The formation of the Drosophila embryonic gonad, involving the fusion of clusters of somatic gonadal precursor cells (SGPs) and their ensheathment of germ cells, provides a simple and genetically tractable model for the interplay between cells during... Read More about Transcriptional regulation of Drosophila gonad formation.

Quantifying the range of a lipid phosphate signal in vivo (2013)
Journal Article
Mukherjee, A., Neher, R. A., & Renault, A. D. (2013). Quantifying the range of a lipid phosphate signal in vivo. Journal of Cell Science, 126(23), 5453-5464. https://doi.org/10.1242/jcs.136176

Quantitative information about the range of influence of extracellular signaling molecules is critical for understanding their effects, but is difficult to determine in the complex and dynamic three-dimensional environment of a living embryo. Drosoph... Read More about Quantifying the range of a lipid phosphate signal in vivo.

Compartmentalizing the embryo: Lipids and septate junction mediated barrier function (2012)
Journal Article
Ile, K. E., & Renault, A. D. (2013). Compartmentalizing the embryo: Lipids and septate junction mediated barrier function. Fly, 7(1), 18-22. https://doi.org/10.4161/fly.22938

Lipid phosphate phosphatases (LPPs) are a class of enzymes that can dephosphorylate a number of lysophopholipids in vitro. Analysis of knockouts of LPP family members has demonstrated striking but diverse developmental roles for these enzymes. LPP3 i... Read More about Compartmentalizing the embryo: Lipids and septate junction mediated barrier function.