All Outputs (3)

Computationally driven design of an artificial metalloenzyme using supramolecular anchoring strategies of iridium complexes to alcohol dehydrogenase (2021)
Journal Article

Artificial metalloenzymes (ArMs) confer non-biological reactivities to biomolecules, whilst taking advantage of the biomolecular architecture in terms of their selectivity and renewable origin. In particular, the design of ArMs by the supramolecular... Read More about Computationally driven design of an artificial metalloenzyme using supramolecular anchoring strategies of iridium complexes to alcohol dehydrogenase.

Oxidation of cadaverine by putrescine oxidase from Rhodococcus erythropolis (2021)
Journal Article

BACKGROUND Putrescine oxidase (EC 1.4.3.10) is of interest for the microbial production of unsubstituted platform nitrogen (N-)heterocycles, because it only requires inexpensive oxygen as co-substrate. Putrescine oxidase from Rhodococcus erythropoli... Read More about Oxidation of cadaverine by putrescine oxidase from Rhodococcus erythropolis.

Design of artificial metalloenzymes for the reduction of nicotinamide cofactors (2021)
Journal Article

Artificial metalloenzymes result from the insertion of a catalytically active metal complex into a biological scaffold, generally a protein devoid of other catalytic functionalities. As such, their design requires efforts to engineer substrate bindin... Read More about Design of artificial metalloenzymes for the reduction of nicotinamide cofactors.