Rational design of thermostable carbonic anhydrase mutants using molecular dynamics simulations
(2018)
Journal Article
Parra-Cruz, R., Jäger, C. M., Lau, P. L., Gomes, R. L., & Pordea, A. (2018). Rational design of thermostable carbonic anhydrase mutants using molecular dynamics simulations. Journal of Physical Chemistry B, 122(36), 8526-8536. https://doi.org/10.1021/acs.jpcb.8b05926
The stability of enzymes is critical for their application in industrial processes, which generally require different conditions from the natural enzyme environment. Both rational and random protein engineering approaches have been used to increase s... Read More about Rational design of thermostable carbonic anhydrase mutants using molecular dynamics simulations.