All Outputs (3)

Differential remodelling in small and large murine airways revealed by novel whole lung airway analysis (2023)
Journal Article
Tatler, A. L., Philp, C. J., Hill, M. R., Cox, S., Bullock, A. M., John, A., …Brook, B. S. (2023). Differential remodelling in small and large murine airways revealed by novel whole lung airway analysis. American Journal of Physiology-Lung Cellular and Molecular Physiology, 324(3), L271-L284. https://doi.org/10.1152/ajplung.00034.2022

Airway remodelling occurs in chronic asthma leading to increased airway smooth muscle (ASM) mass and extra-cellular matrix (ECM) deposition. Whilst extensively studied in murine airways, studies report only selected larger airways at one time point m... Read More about Differential remodelling in small and large murine airways revealed by novel whole lung airway analysis.

Plasma cells: a feasible therapeutic target in pulmonary fibrosis? (2022)
Journal Article
Goodwin, A. T., Noble, P. W., & Tatler, A. L. (2022). Plasma cells: a feasible therapeutic target in pulmonary fibrosis?. European Respiratory Journal, 60(5), Article 2201748. https://doi.org/10.1183/13993003.01748-2022

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease characterised by the irreversible replacement of normal lung parenchyma with stiff scar tissue. The prognosis of IPF is very poor, with a median survival worse than many canc... Read More about Plasma cells: a feasible therapeutic target in pulmonary fibrosis?.

Highlights of the ERS Lung Science Conference and Sleep and Breathing Conference 2021 and the new ECMC members (2021)
Journal Article
Goodwin, A. T., Karadoğan, D., De Santis, M. M., Alsafadi, H. N., Hawthorne, I., Bradicich, M., …Cruz, J. (2021). Highlights of the ERS Lung Science Conference and Sleep and Breathing Conference 2021 and the new ECMC members. Breathe, 17(3), Article 210080. https://doi.org/10.1183/20734735.0080-2021

The Lung Science Conference (LSC) and the Sleep and Breathing Conference (SBC) are two conferences organised by the European Respiratory Society (ERS), the latter held in association with the European Sleep Research Society. This year, the LSC and SB... Read More about Highlights of the ERS Lung Science Conference and Sleep and Breathing Conference 2021 and the new ECMC members.