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Structure of the human Ccr4-Not nuclease module using X-ray crystallography and electron paramagnetic resonance spectroscopy distance measurements (2021)
Journal Article

Regulated degradation of mature, cytoplasmic mRNA is a key step in eukaryotic gene regulation. This process is typically initiated by the recruitment of deadenylase enzymes by cis-acting elements in the 3' untranslated region resulting in the shorten... Read More about Structure of the human Ccr4-Not nuclease module using X-ray crystallography and electron paramagnetic resonance spectroscopy distance measurements.

Application of DNP-enhanced solid-state NMR to studies of amyloid-? peptide interaction with lipid membranes (2021)
Journal Article

The cellular membrane disruption induced by the aggregation of Aβ peptide has been proposed as a plausible cause of neuronal cell death during Alzheimer’s disease. The molecular-level details of the Aβ interaction with cellular membranes were previou... Read More about Application of DNP-enhanced solid-state NMR to studies of amyloid-? peptide interaction with lipid membranes.

Application of spherical harmonics for DEER data analysis in systems with a conformational distribution (2020)
Journal Article

Double electron–electron resonance (DEER) and other pulse electron paramagnetic resonance (EPR) techniques are valuable tools for determining distances between paramagnetic centres. DEER theory is well developed for a scenario where relative orientat... Read More about Application of spherical harmonics for DEER data analysis in systems with a conformational distribution.