All Outputs (4)

A diverse panel of hepatitis C virus glycoproteins for use in vaccine research reveals extremes of monoclonal antibody neutralization resistance (2015)
Journal Article
Urbanowicz, R. A., McClure, P., Brown, R. J., Tsoleridis, T., Persson, M. A., Krey, T., …Tarr, A. W. (2016). A diverse panel of hepatitis C virus glycoproteins for use in vaccine research reveals extremes of monoclonal antibody neutralization resistance. Journal of Virology, 90(7), 3288-3301. https://doi.org/10.1128/JVI.02700-15

Despite significant advances in the treatment of hepatitis C virus (HCV) infection, the need to develop preventative vaccines remains. Identification of the best vaccine candidates and evaluation of their performance in preclinical and clinical devel... Read More about A diverse panel of hepatitis C virus glycoproteins for use in vaccine research reveals extremes of monoclonal antibody neutralization resistance.

Genetic diversity underlying the envelope glycoproteins of hepatitis C virus: Structural and functional consequences and the implications for vaccine design (2015)
Journal Article
Tarr, A. W., Khera, T., Hueging, K., Sheldon, J., Steinmann, E., Pietschmann, T., & Brown, R. J. (2015). Genetic diversity underlying the envelope glycoproteins of hepatitis C virus: Structural and functional consequences and the implications for vaccine design. Viruses, 7(7), 3995-4046. https://doi.org/10.3390/v7072809

© 2015 by the authors. In the 26 years since the discovery of Hepatitis C virus (HCV) a major global research effort has illuminated many aspects of the viral life cycle, facilitating the development of targeted antivirals. Recently, effective direct... Read More about Genetic diversity underlying the envelope glycoproteins of hepatitis C virus: Structural and functional consequences and the implications for vaccine design.

Non-ionic detergents facilitate non-specific binding of M13 bacteriophage to polystyrene surfaces (2015)
Journal Article
Hakami, A. R., Ball, J. K., & Tarr, A. W. (2015). Non-ionic detergents facilitate non-specific binding of M13 bacteriophage to polystyrene surfaces. Journal of Virological Methods, 221, 1-8. https://doi.org/10.1016/j.jviromet.2015.04.023

© 2015 Elsevier B.V. Phage-displayed random peptide libraries are widely used for identifying peptide interactions with proteins and other substrates. Selection of peptide ligands involves iterative rounds of affinity enrichment. The binding properti... Read More about Non-ionic detergents facilitate non-specific binding of M13 bacteriophage to polystyrene surfaces.

Human lectins and their roles in viral infections (2015)
Journal Article
Mason, C. P., & Tarr, A. W. (2015). Human lectins and their roles in viral infections. Molecules, 20(2), 2229-2271. https://doi.org/10.3390/molecules20022229

© 2015 by the authors; licensee MDPI. Innate recognition of virus proteins is an important component of the immune response to viral pathogens. A component of this immune recognition is the family of lectins; pattern recognition receptors (PRRs) that... Read More about Human lectins and their roles in viral infections.