All Outputs (5)

Approaches to risk ratio estimation in a regression discontinuity design: Application to the prescription of statins for cholesterol reduction in UK primary care (2023)
Journal Article
Adeleke, M. O., O’Keeffe, A. G., & Baio, G. (2023). Approaches to risk ratio estimation in a regression discontinuity design: Application to the prescription of statins for cholesterol reduction in UK primary care. Statistical Methods in Medical Research, 32(10), 1994-2015. https://doi.org/10.1177/09622802231192958

In recent years regression discontinuity designs have been used increasingly for the estimation of treatment effects in observational medical data where a rule-based decision to apply treatment is taken using a continuous assignment variable. Most re... Read More about Approaches to risk ratio estimation in a regression discontinuity design: Application to the prescription of statins for cholesterol reduction in UK primary care.

Protocol for the feasibility and implementation study of a model of best practice in primary care led postdiagnostic dementia care: PriDem. (2023)
Journal Article
Griffiths, S., Spencer, E., Wilcock, J., Bamford, C., Wheatley, A., Brunskill, G., …Rait, G. (2023). Protocol for the feasibility and implementation study of a model of best practice in primary care led postdiagnostic dementia care: PriDem. BMJ Open, 13(8), Article e070868. https://doi.org/10.1136/bmjopen-2022-070868

Introduction: Care is often inadequate and poorly integrated after a dementia diagnosis. Research and policy highlight the unaffordability and unsustainability of specialist-led support, and instead suggest a task-shared model, led by primary care. T... Read More about Protocol for the feasibility and implementation study of a model of best practice in primary care led postdiagnostic dementia care: PriDem..

The impact of temporal lobe epilepsy surgery on picture naming and its relationship to network metric change. (2023)
Journal Article
Peter Binding, L., Neal Taylor, P., O'Keeffe, A. G., Giampiccolo, D., Fleury, M., Xiao, F., …Vos, S. B. (2023). The impact of temporal lobe epilepsy surgery on picture naming and its relationship to network metric change. NeuroImage: Clinical, 38, Article 103444. https://doi.org/10.1016/j.nicl.2023.103444

Background: Anterior temporal lobe resection (ATLR) is a successful treatment for medically-refractory temporal lobe epilepsy (TLE). In the language-dominant hemisphere, 30%- 50% of individuals experience a naming decline which can impact upon daily... Read More about The impact of temporal lobe epilepsy surgery on picture naming and its relationship to network metric change..

Contribution of White Matter Fiber Bundle Damage to Language Change After Surgery for Temporal Lobe Epilepsy (2023)
Journal Article
Binding, L. P., Dasgupta, D., Taylor, P. N., Thompson, P. J., O'Keeffe, A. G., De Tisi, J., …Vos, S. B. (2023). Contribution of White Matter Fiber Bundle Damage to Language Change After Surgery for Temporal Lobe Epilepsy. Neurology, 100(15), e1621-e1633. https://doi.org/10.1212/WNL.0000000000206862

Background and ObjectivesIn medically refractory temporal lobe epilepsy (TLE), 30%-50% of patients experience substantial language decline after resection in the language-dominant hemisphere. In this study, we investigated the contribution of white m... Read More about Contribution of White Matter Fiber Bundle Damage to Language Change After Surgery for Temporal Lobe Epilepsy.

Hippocampal resection in temporal lobe epilepsy: Do we need to resect the tail? (2023)
Journal Article
Dasgupta, D., Finn, R., Chari, A., Giampiccolo, D., de Tisi, J., O’Keeffe, A. G., …Duncan, J. S. (2023). Hippocampal resection in temporal lobe epilepsy: Do we need to resect the tail?. Epilepsy Research, 190, Article 107086. https://doi.org/10.1016/j.eplepsyres.2023.107086

Introduction: Anteromesial temporal lobe resection is the most common surgical technique used to treat drug-resistant mesial temporal lobe epilepsy, particularly when secondary to hippocampal sclerosis. Structural and functional imaging data suggest... Read More about Hippocampal resection in temporal lobe epilepsy: Do we need to resect the tail?.