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All Outputs (86)

National Early Warning Scores Following Emergency Hospital Transfer: Implications for Care Home Residents (2023)
Journal Article

Objective: Care home residents have high rates of hospital admission. The UK National Early Warning Score (NEWS2) standardizes the secondary care response to acute illness. However, the ability of NEWS2 to predict adverse health outcomes specifically... Read More about National Early Warning Scores Following Emergency Hospital Transfer: Implications for Care Home Residents.

Dietary nitrate supplementation for preventing and reducing the severity of winter infections, including COVID-19, in care homes (BEET-Winter)-a randomised placebo-controlled feasibility trial (2022)
Journal Article

Purpose Infections cause considerable care home morbidity and mortality. Nitric oxide (NO) has broad-spectrum anti-viral, bacterial and yeast activity in vitro. We assessed the feasibility of supplementing dietary nitrate (NO substrate) intake in ca... Read More about Dietary nitrate supplementation for preventing and reducing the severity of winter infections, including COVID-19, in care homes (BEET-Winter)-a randomised placebo-controlled feasibility trial.

Development of a core outcome set for the evaluation of interventions to prevent COVID-19 in care homes (COS-COVID-PCARE Study) (2022)
Journal Article

Background: People living in care homes have experienced devastating impact from COVID-19. As interventions to prevent the transmission of COVID-19 are developed and evaluated, there is an urgent need for researchers to agree on the outcomes used whe... Read More about Development of a core outcome set for the evaluation of interventions to prevent COVID-19 in care homes (COS-COVID-PCARE Study).

'Don't let the trial kill the intervention': how can researchers and care home teams implement complex intervention trials in care homes? (2022)
Journal Article

The profile of care homes has never been higher, and not necessarily for the best reasons[1]. The COVID-19 pandemic has had, and continues to have, a massive impact on care home residents[2] , their families, the staff and organisations who care for... Read More about 'Don't let the trial kill the intervention': how can researchers and care home teams implement complex intervention trials in care homes?.

Developing a minimum data set for older adult care homes in the UK: exploring the concept and defining early core principles (2022)
Journal Article

Reforms to social care in response to the COVID-19 pandemic, in the UK and internationally, place data at the heart of proposed innovations and solutions. The principles are not well established of what constitutes core, or minimum, data to support c... Read More about Developing a minimum data set for older adult care homes in the UK: exploring the concept and defining early core principles.

Contextual factors influencing complex intervention research processes in care homes: A systematic review and framework synthesis (2022)
Journal Article

Background: Care homes are complex settings to undertake intervention research. Barriers to research implementation processes can threaten studies' validity, reducing the value to residents, staff, researchers and funders. We aimed to (i) identify an... Read More about Contextual factors influencing complex intervention research processes in care homes: A systematic review and framework synthesis.

Effect of perindopril or leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial (2022)
Journal Article

BACKGROUND: This trial aimed to determine the efficacy of leucine and/or perindopril in improving physical function in older people with sarcopenia. METHODS: Placebo-controlled, parallel group, double-blind, randomized two-by-two factorial trial. We... Read More about Effect of perindopril or leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial.

The uptake and use of a minimum data set (MDS) for older people living and dying in care homes: a realist review (2022)
Journal Article

Background: Care homes provide long term care for older people. Countries with standardised approaches to residents’ assessment, care planning and review (known as minimum data sets (MDS)) use the aggregate data to guide resource allocation, monitor... Read More about The uptake and use of a minimum data set (MDS) for older people living and dying in care homes: a realist review.

Which factors influence the prevalence of institution-acquired falls? Results from an international, multi-center, cross-sectional survey (2021)
Journal Article

Purpose: Falls are a highly prevalent problem in hospitals and nursing homes with serious negative consequences such as injuries, increased care dependency, or even death. The aim of this study was to provide a comprehensive insight into institution-... Read More about Which factors influence the prevalence of institution-acquired falls? Results from an international, multi-center, cross-sectional survey.

Multifactorial falls prevention programme compared with usual care in UK care homes for older people: Multicentre cluster randomised controlled trial with economic evaluation (2021)
Journal Article

Objectives To determine the clinical and cost effectiveness of a multifactorial fall prevention programme compared with usual care in long term care homes. Design Multicentre, parallel, cluster randomised controlled trial. Setting Long term care home... Read More about Multifactorial falls prevention programme compared with usual care in UK care homes for older people: Multicentre cluster randomised controlled trial with economic evaluation.

Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol (2021)
Working Paper

Introduction There is a high prevalence of frailty and cognitive impairment within care home population. These wide-ranging experiences and needs impact on residents’ quality of life. Therefore, measuring Quality of Life (QOL) in residents as part... Read More about Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol.

Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol (2021)
Working Paper

East Midlands Research into Ageing Network (EMRAN) is a research collaboration across the East Midlands to facilitate collaborative applied clinical research into ageing and the care of older people. EMRAN was set up by NIHR CLAHRC East Midlands and... Read More about Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol.