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All Outputs (90)

Incident gout and erectile dysfunction: is hyperuricaemia the elephant in the room? (2017)
Journal Article
Abhishek, A., & Doherty, M. (2017). Incident gout and erectile dysfunction: is hyperuricaemia the elephant in the room?. Arthritis Research and Therapy, 19, Article 184. https://doi.org/10.1186/s13075-017-1394-x

The first prospective population-based study to examine risk of erectile dysfunction in men with gout in the western world has been published. It reports that following their first diagnosis of gout, men have a 31% higher risk of erectile dysfunction... Read More about Incident gout and erectile dysfunction: is hyperuricaemia the elephant in the room?.

Association of beta-blocker use with less prevalent joint pain and lower opioid requirement in people with osteoarthritis (2017)
Journal Article
Valdes, A. M., Abhishek, A., Muir, K., Zhang, W., Maciewicz, R. A., & Doherty, M. (2017). Association of beta-blocker use with less prevalent joint pain and lower opioid requirement in people with osteoarthritis. Arthritis Care and Research, 69(7), 1076-1081. https://doi.org/10.1002/acr.23091

Objective: Recent findings suggest that β-adrenergic blockers have anti-nociceptive properties. The aim of this study was to compare levels of large joint pain between those on adrenergic blockers and those on other antihypertensive medications.
Met... Read More about Association of beta-blocker use with less prevalent joint pain and lower opioid requirement in people with osteoarthritis.

First validation of the gout activity score against gout impact scale in a primary care based gout cohort (2017)
Journal Article
La-Crette, J., Jenkins, W., Fernandes, G. S., Valdes, A. M., Doherty, M., & Abhishek, A. (in press). First validation of the gout activity score against gout impact scale in a primary care based gout cohort. Joint Bone Spine, https://doi.org/10.1016/j.jbspin.2017.05.010

Objectives To validate the gout activity score (GAS) against the gout impact scale in a primary care based gout cohort.
Methods This was a single-centre cross-sectional study. People with gout who participated in previous research at Academic Rheuma... Read More about First validation of the gout activity score against gout impact scale in a primary care based gout cohort.

Rheumatoid arthritis is getting less frequent—results of a nationwide population-based cohort study (2017)
Journal Article
Abhishek, A., Doherty, M., Kuo, C.-F., Mallen, C. D., Zhang, W., & Grainge, M. J. (2017). Rheumatoid arthritis is getting less frequent—results of a nationwide population-based cohort study. Rheumatology, 56(5), 736-744. https://doi.org/10.1093/rheumatology/kew468

Objectives: The objectives of this study were to examine changes in incidence and prevalence of RA between 1990 and 2014, and to explore if there is any geographic variation in incidence and prevalence of RA in the UK
Methods:
Design Prospective... Read More about Rheumatoid arthritis is getting less frequent—results of a nationwide population-based cohort study.

Long-term persistence and adherence on urate-lowering treatment can be maintained in primary care-5-year follow-up of a proof-of-concept study (2016)
Journal Article
Abhishek, A., Jenkins, W., La-Crette, J., Fernandes, G. S., & Doherty, M. (2016). Long-term persistence and adherence on urate-lowering treatment can be maintained in primary care-5-year follow-up of a proof-of-concept study. Rheumatology, 56(4), https://doi.org/10.1093/rheumatology/kew395

Objectives: To evaluate the persistence and adherence on urate-lowering treatment (ULT) in primary care 5 years after an initial nurse-led treatment of gout.

Methods: One hundred gout patients initiated on up-titrated ULT between March and July 20... Read More about Long-term persistence and adherence on urate-lowering treatment can be maintained in primary care-5-year follow-up of a proof-of-concept study.

Does the initiation of urate-lowering treatment during an acute gout attack prolong the current episode and precipitate recurrent attacks: a systematic literature review (2016)
Journal Article
Eminaga, F., Le-Carratt, J., Jones, A., & Abhishek, A. (2016). Does the initiation of urate-lowering treatment during an acute gout attack prolong the current episode and precipitate recurrent attacks: a systematic literature review. Rheumatology International, 36(12), 1747-1752. https://doi.org/10.1007/s00296-016-3579-z

Objectives:

To systematically review the literature on effect of initiating urate lowering treatment (ULT) during an acute attack of gout on duration of index attack and persistence on ULT.

Methods:

OVID (MEDLINE), EMBASE and AMED were sea... Read More about Does the initiation of urate-lowering treatment during an acute gout attack prolong the current episode and precipitate recurrent attacks: a systematic literature review.

Adequacy of Online Patient Information Resources on Gout and Potentially Curative Urate-Lowering Treatment (2016)
Journal Article
Jimenez-Liñan, L. M., Edwards, L., Abhishek, A., & Doherty, M. (2017). Adequacy of Online Patient Information Resources on Gout and Potentially Curative Urate-Lowering Treatment. Arthritis Care and Research, 69(5), 748-752. https://doi.org/10.1002/acr.22981

© 2016, American College of Rheumatology Objective: To assess the content and readability of online patient information resources against the current understanding of gout. Methods: An online survey was undertaken using Google UK, USA, Australia, and... Read More about Adequacy of Online Patient Information Resources on Gout and Potentially Curative Urate-Lowering Treatment.

The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study (2014)
Journal Article
Doherty, S., Zhang, W., Maciewicz, R., Doherty, M., Muir, K., Abhishek, A., & Valdes, A. M. (2014). The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study. Arthritis Research and Therapy, 16(1), Article R25. https://doi.org/10.1186/ar4453

Introduction
Chondrocalcinosis (CC) most commonly results from calcium pyrophosphate crystal deposition (CPPD). The objective of this study is to examine the association between candidate single-nucleotide polymorphisms (SNPs) and radiographic CC.... Read More about The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study.

Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study (2013)
Journal Article
Doherty, S., Doherty, M., Maciewicz, R., Abhishek, A., Muir, K., & Zhang, W. (2014). Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study. Annals of the Rheumatic Diseases, 73(11), 1997-2002. https://doi.org/10.1136/annrheumdis-2013-203400